FolkKB

cockspurthorn

Maclura cochinchinensis

Maclura cochinchinensis，又称中国纸木棉，是一种传统上在东亚医学中使用的植物。尽管其具体的传统用途没有很好地记录下来，但研究表明，含有原花青素和氧原花青素的心材提取物可以显著抑制B16F10黑色素瘤细胞的黑色素生成。此外，乙酸乙酯和n-己烷提取物以及从Maclura cochinchinensis中获得的原花青素还表现出对白血病细胞具有显著的细胞毒性、抗氧化性、抗炎性和抗迁移活性。合成的toxyloxanthone C和macluraxanthone衍生物也显示出对癌细胞的细胞毒性和抗菌活性。科学证据表明，这种植物可能在抑制黑色素瘤和抗癌方面具有潜在的好处，但需要更多的研究来得出明确的结论。没有记录到主要的安全问题或药物相互作用，尽管进一步的研究对于完全了解其效果和应用是必要的。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 来自马尔拉科钦辛尼森树心材的提取物含有白藜芦醇和氧白藜芦醇，显著抑制B16F10黑色素瘤细胞中的黑色素生成。 D PMID
  • 研究发现，来自马克拉拉科希尼辛（Maclura cochinchinensis）的乙酸乙酯和n-己烷提取物以及原花青素表现出显著的细胞毒性、抗氧化性、抗炎性和迁移抑制活性，对抗白血病细胞。 D PMID
  • 从Macrura cochinchinensis合成的Lupalbigenin显示出快速杀菌活性并抑制了生物膜形成。 D PMID
  • 研究合成了来自Maclura cochinchinensis的托昔氧黄酮C和马库拉氧黄酮衍生物，其中一些表现出对癌细胞的细胞毒性以及抗菌活性。 D PMID

Frequently asked questions

What is cockspurthorn?

cockspurthorn (Maclura cochinchinensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about cockspurthorn?

4 sourced findings are recorded for cockspurthorn; the strongest carries evidence grade D. For example: 来自马尔拉科钦辛尼森树心材的提取物含有白藜芦醇和氧白藜芦醇，显著抑制B16F10黑色素瘤细胞中的黑色素生成。

How strong is the evidence for cockspurthorn?

The strongest finding for cockspurthorn carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is cockspurthorn safe? What are the side effects?

No major safety issues are recorded for cockspurthorn in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does cockspurthorn interact with medications?

No drug interactions are recorded for cockspurthorn in our sources. This does not rule them out — check with a pharmacist.

Is cockspurthorn a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Biological activities of extracts and compounds from Thai Kae-Lae (Maclura cochinchinensis (Lour.) Corner). literature abstract metadata
  2. T2 Maclura cochinchinensis (Lour.) Corner Heartwood Extracts Containing Resveratrol and Oxyresveratrol Inhibit Melanogenesis in B16F10 Melanoma Cells. literature abstract metadata
  3. T2 Total synthesis and antibacterial evaluation of lupalbigenin and isolupalbigenin. literature abstract metadata
  4. T2 Structural modifications of toxyloxanthone C and macluraxanthone isolated from Maclura cochinchinensis: cytotoxicity, antibacterial activity, and in silico studies. literature abstract metadata