Japanese Big Leaf Magnolia
Magnolia obovata
木兰属卵形种是一种传统草药，原产于东亚。尽管其在传统实践中的具体用途尚未得到充分记录，但研究表明通过将木兰醇和Honokiol整合到静电纺丝纤维中，该植物具有增强抗氧化和抗菌活性的潜在生物活动。研究还表明，放射性铯可以通过食用从木兰属卵形种叶片转移到幼虫体内，并在幼虫粪便中发现较高浓度。体外研究表明，该植物中的化合物可以诱导乳腺癌细胞凋亡并下调PI3K/Akt通路，同时识别了组织特异性积累活性成分如Honokiol和Magnolol以及参与其生物合成的候选基因。迄今为止，尚未报告有关木兰属卵形种的重大安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 这项研究开发了β-环糊精-寡乳酸电纺纤维，以纳入木兰脂素和厚朴酚，从而增强其抗氧化和抗菌活性。
- 木贼叶中的放射性铯转移到幼虫中是通过摄取实现的，幼虫粪便中发现了较高浓度。
- 来自Magnolia obovata的Ob通过下调PI3K/Akt途径诱导了乳腺癌细胞的凋亡。
- 该研究识别出了特定组织中生物活性化合物（包括新木脂素）在Magnolia obovata中的积累，并提出了参与其生物合成的候选基因。
Frequently asked questions
What is Japanese Big Leaf Magnolia?
Japanese Big Leaf Magnolia (Magnolia obovata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Japanese Big Leaf Magnolia?
4 sourced findings are recorded for Japanese Big Leaf Magnolia; the strongest carries evidence grade D. For example: 这项研究开发了β-环糊精-寡乳酸电纺纤维，以纳入木兰脂素和厚朴酚，从而增强其抗氧化和抗菌活性。
How strong is the evidence for Japanese Big Leaf Magnolia?
The strongest finding for Japanese Big Leaf Magnolia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Japanese Big Leaf Magnolia safe? What are the side effects?
No major safety issues are recorded for Japanese Big Leaf Magnolia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Japanese Big Leaf Magnolia interact with medications?
No drug interactions are recorded for Japanese Big Leaf Magnolia in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Japanese Big Leaf Magnolia?
Japanese Big Leaf Magnolia is also known as: Магнолия обратнояйцевидная.
Is Japanese Big Leaf Magnolia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Polymer-Free Electrospinning of β-Cyclodextrin-Oligolactide for Magnolol and Honokiol Pharmaceutical Formulations. literature abstract metadata
- T2 Multi-Omics Analysis Decodes Biosynthesis of Specialized Metabolites Constituting the Therapeutic Terrains of Magnolia obovata. literature abstract metadata
- T2 Role of shredders in the transfer of radiocesium from leaflitter to headwater stream ecosystems in temperate forests. literature abstract metadata
- T2 Obovatol induces apoptosis in breast cancer by downregulating the PI3K/Akt pathway. literature abstract metadata