Rajmahal-creeper
Marsdenia tenacissima
马尔森尼亚坚牢（Marsdenia tenacissima）是一种传统上在中国医学中使用的植物，特别是在中国和韩国的传统实践中。研究表明它具有潜在的抗癌作用，并可能增强某些类型癌症化疗的效果。具体而言，研究显示将马尔森尼亚坚牢与化疗结合使用可以提高晚期非小细胞肺癌（NSCLC）患者的客观缓解率。此外，从该植物中分离出的甾体苷表现出对CYP3A4酶活性的显著抑制作用，并显示出作为标准化疗辅助治疗胃癌的潜力。然而，现有证据仍然存在异质性，表明需要进一步研究。没有记录到主要的安全问题或药物相互作用，但由于临床数据有限，仍需谨慎。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Marsdenia tenacissima与化疗联合使用在晚期NSCLC中显示出客观反应率提高的效果。
- Seven undescribed steroidal glycosides were isolated from Marsdenia tenacissima and showed statistically significant inhibitory effects on CYP3A4 enzymatic activity.
- Tongguanteng 注射液通过靶向 AURKA/KEAP1/NRF2 轴在乳腺癌细胞中诱导 G2/M 期阻滞和铁死亡。
- 马尔森尼亚十齿花的植物化合物显示出作为胃癌标准化疗辅助治疗的潜力，尽管证据仍然存在异质性。
Frequently asked questions
What is Rajmahal-creeper?
Rajmahal-creeper (Marsdenia tenacissima) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Rajmahal-creeper?
4 sourced findings are recorded for Rajmahal-creeper; the strongest carries evidence grade A. For example: Marsdenia tenacissima与化疗联合使用在晚期NSCLC中显示出客观反应率提高的效果。
How strong is the evidence for Rajmahal-creeper?
The strongest finding for Rajmahal-creeper carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Rajmahal-creeper safe? What are the side effects?
No major safety issues are recorded for Rajmahal-creeper in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Rajmahal-creeper interact with medications?
No drug interactions are recorded for Rajmahal-creeper in our sources. This does not rule them out — check with a pharmacist.
Is Rajmahal-creeper a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Economics, efficacy and safety of five traditional Chinese medicine injections plus chemotherapy as adjuvant therapy for non-small cell lung cancer: A network meta-analysis. literature abstract metadata
- T2 Synergistic Interactions Between Medicinal Plant Bioactive and Standard Chemotherapy in Gastric Cancer: Preclinical Evidence and Translational Pitfalls. literature abstract metadata
- T2 Tongguanteng injection induces cell cycle arrest and drives ferroptosis through AURKA/KEAP1/NRF2 axis in breast cancer. literature abstract metadata
- T2 Seven undescribed steroidal glycosides with CYP3A4 inhibitory activity from the stems of Marsdenia tenacissima. literature abstract metadata