Chinese Peony
Paeonia lactiflora
白芍（Paeonia lactiflora）在传统中医中被称为白芍药或白芍，常用于调节血液和缓解疼痛。尽管具体的用途可能因不同的传统而异，但这种植物已经在东方的实践中使用了几个世纪。科学研究表明，芍药苷，存在于Paeonia lactiflora中的化合物，可以增强巨噬细胞中SOCS3的表达，从而在骨关节炎模型中潜在地减少炎症。此外，从该植物衍生的外泌体显示出改善糖尿病周围神经病变的前景，通过调节CCL21/CCR7轴并减少施万细胞损伤和神经炎症。其他研究表明，另一种化合物白花苷可以从Paeonia lactiflora中降低肾癌细胞的存活率、增殖和迁移，通过抑制EGFR/MAPK信号通路，具有多种药理作用包括抗炎、神经保护和肝保护效果。然而，由于临床数据有限，其口服生物利用度仍不确定。迄今为止尚未发现白芍的主要安全问题或记录的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 白花前胡素上调巨噬细胞中SOCS3的表达，可能在OA小鼠模型中减少炎症。
- 从白芍提取的外泌体通过调节CCL21/CCR7轴改善糖尿病周围神经病变，减少施万细胞损伤和神经炎症。
- Albiflorin 通过部分抑制 EGFR/MAPK 信号通路，降低了肾细胞癌细胞的存活率、增殖和迁移。
- 阿尔比弗林显示出多种药理活性，包括抗炎、神经保护和肝保护作用，但最佳口服生物利用度仍不确定。
- 三个品种‘Red Charm’、‘Bartzella’和‘Sarah Bernhardt’在严重压力下显示出更强的相对盐碱耐受性。
- 从白芍根中鉴定出三种新的单萜，大多数显示出对H2O2诱导的PC12细胞损伤具有显著的神经保护作用。
Frequently asked questions
What is Chinese Peony?
Chinese Peony (Paeonia lactiflora) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese Peony?
6 sourced findings are recorded for Chinese Peony; the strongest carries evidence grade D. For example: 白花前胡素上调巨噬细胞中SOCS3的表达，可能在OA小鼠模型中减少炎症。
How strong is the evidence for Chinese Peony?
The strongest finding for Chinese Peony carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese Peony safe? What are the side effects?
No major safety issues are recorded for Chinese Peony in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese Peony interact with medications?
No drug interactions are recorded for Chinese Peony in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese Peony?
Chinese Peony is also known as: Пион молочноцветковый, Pivoine de Chine.
Is Chinese Peony a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Integrated experimental and network pharmacology analyses reveal inhibitory effects of albiflorin on renal cell carcinoma cells. literature abstract metadata
- T2 Paeonia lactiflora-derived extracellular vesicles ameliorate diabetic peripheral neuropathy by modulating chemokine-guided immune trafficking in peripheral nerves. literature abstract metadata
- T2 Monoterpenoids from the roots of Paeonia lactiflora Pall. and their neuroprotective activity. literature abstract metadata
- T2 Paeoniflorin elevates the expression of SOCS3 in macrophages to prevent MIA-induced osteoarthritis in mice. literature abstract metadata
- T2 Evaluation and physiological response of peony (Paeonia lactiflora Pall.) under salt stress. literature abstract metadata
- T2 A Review of the Pharmacodynamics and Pharmacokinetics of Albiflorin. literature abstract metadata