Grecian Silkvine

Periploca graeca

Periploca graeca 是一种传统草药,起源于小亚细亚和地中海。其在民间医学中的使用尚未广泛记录,但具有历史意义。科学研究表明,从 Periploca graeca 中提取的 periplocymarin 不与 P-糖蛋白或主要的细胞色素 P450 酶发生显著相互作用,这表明其可能对药物相互作用安全。在植物中鉴定出的卡定诺利德表现出针对白血病和前列腺癌细胞的促凋亡和细胞抑制效应,暗示潜在的治疗应用。从九种测试的卡定诺利德中,有五种显示出强烈的抗增殖活性对抗 PC-3 细胞,同时还发现了六种新的孕烷糖苷,包括硫酸衍生物。迄今为止,尚未报告 Periploca graeca 有任何重大安全问题或药物相互作用。

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 珀里普洛克辛arin高度渗透且不与P-糖蛋白或主要细胞色素P450酶相互作用。 D PMID
  • 紫藤卡定类化合物在白血病和前列腺癌细胞中表现出促凋亡和细胞抑制作用,具有不同的机制。 D PMID
  • 从Periploca graeca中鉴定出的9种卡定诺利德中有5种对PC-3细胞显示出强烈的抗增殖作用。 D PMID
  • 从Periploca graeca中鉴定出六种新的孕烷苷,包括硫酸衍生物。 D PMID

Frequently asked questions

What is Grecian Silkvine?

Grecian Silkvine (Periploca graeca) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Grecian Silkvine?

4 sourced findings are recorded for Grecian Silkvine; the strongest carries evidence grade D. For example: 珀里普洛克辛arin高度渗透且不与P-糖蛋白或主要细胞色素P450酶相互作用。

How strong is the evidence for Grecian Silkvine?

The strongest finding for Grecian Silkvine carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Grecian Silkvine safe? What are the side effects?

No major safety issues are recorded for Grecian Silkvine in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Grecian Silkvine interact with medications?

No drug interactions are recorded for Grecian Silkvine in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Grecian Silkvine?

Grecian Silkvine is also known as: Обвойник греческий, Bourreau-des-arbres.

Is Grecian Silkvine a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Sulfated pregnane glycosides from Periploca graeca. literature abstract metadata
  2. T2 Antiproliferative cardenolides from Periploca graeca. literature abstract metadata
  3. T2 Pro-apoptotic and cytostatic activity of naturally occurring cardenolides. literature abstract metadata
  4. T2 Periplocymarin is a potential natural compound for drug development: highly permeable with absence of P-glycoprotein efflux and cytochrome P450 inhibitions. literature abstract metadata