Chinese silk vine
Periploca sepium
Periploca sepium，也称为中国铁线莲或攀援假大戟，源自传统中医（TCM），在中国的多个地区都有发现。传统上，它并未广泛用于特定的医疗用途。然而，最近的科学研究已经识别出两个基因PsCYP87和Ps14βPH参与植物中卡登诺利德生物合成，这可能表明了潜在的进化机制。此外，Periploca sepium 的根油显示出对蘑菇酪氨酸酶多酚酶活性的选择性抑制作用，同时保留单酚酶活性，暗示其可能与皮肤相关的应用。虽然有九项研究建议Longdan Xiegan方剂（其中包括Periploca sepium等其他草药）可能有助于管理高血压症状和风险因素，但这些证据基于元分析的综合，并需要进一步高质量的研究来确认这些发现。涉及Periploca sepium的传统中医干预措施已被证明可以显著改善糖尿病足溃疡（DFU）相关的结果，这在元分析的综合中得到了证实。对于这种植物尚未记录主要的安全问题或药物相互作用，尽管仍需进行全面的临床试验以全面了解其潜在的好处和风险。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 九项研究提示龙胆泻肝方可能有助于管理高血压症状和风险因素，但需要高质量的研究。
- 研究鉴定出两个基因PsCYP87和Ps14βPH参与了Periploca sepium中的卡定诺利德生物合成，突显了不同的进化机制。
- Periploca sepium 根油选择性地抑制了蘑菇多酚氧化酶活性，同时保留了一元酚氧化酶的活性。
- 研究发现，Periploca sepium 在不同光照环境中表现出不同的枝条和叶片形态以及光合特性，反映了适应策略。
- 研究发现，中医疗法无论是外用还是口服，都能显著改善DFU相关的结果，包括溃疡面积减小和愈合时间缩短。
Frequently asked questions
What is Chinese silk vine?
Chinese silk vine (Periploca sepium) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese silk vine?
5 sourced findings are recorded for Chinese silk vine; the strongest carries evidence grade A. For example: 九项研究提示龙胆泻肝方可能有助于管理高血压症状和风险因素，但需要高质量的研究。
How strong is the evidence for Chinese silk vine?
The strongest finding for Chinese silk vine carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese silk vine safe? What are the side effects?
No major safety issues are recorded for Chinese silk vine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese silk vine interact with medications?
No drug interactions are recorded for Chinese silk vine in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese silk vine?
Chinese silk vine is also known as: Обвойник заборный, périploque de Chine.
Is Chinese silk vine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Traditional Chinese medicine in the management of diabetic foot ulcers: an overview of meta-analyses. literature abstract metadata
- T2 Periploca root oils as potent, diphenolase-selective tyrosinase inhibitors: chemotype profiling and non-competitive mechanism of 4-methoxy-2-hydroxybenzaldehyde. literature abstract metadata
- T2 Twig and Leaf Morphological Traits and Photosynthetic Physiological Characteristics of Periploca sepium in Response to Different Light Environments in Taohe Riparian Forests. literature abstract metadata
- T2 Plastid 2-oxoglutarate-dependent dioxygenases mediate stereoselective C14β-hydroxylation in cardenolide biosynthesis. literature abstract metadata
- T2 Longdan Xiegan formula as adjuvant therapy for hypertension: A systematic review and meta-analysis. literature abstract metadata