FolkKB

Physochlaina

Physochlaina

Physochlaina，一种传统草药，主要来源于其根部，并在少数有记录的实践中被传统使用。科学研究表明，Physochlaina physaloides 在通过优化超声辅助提取总黄酮对宫颈癌HeLa细胞表现出的细胞毒性方面显示出令人鼓舞的结果。此外，Physochloside D 调节 JAK2/STAT3 信号通路以抑制 CAG 模型中的凋亡和肠化生。该植物还产生了九种新的甾体皂苷，其中 infundilide A 在细胞培养和小鼠模型中均表现出抗炎作用。此外，Physochlaina physaloides 的 n-丁醇提取物在大鼠中通过调节 PPAR/NF-κB 信号通路对胃损伤具有保护作用。迄今为止，尚未发现该植物存在重大安全问题或记录的药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 物理霍醇D，来自P. physaloides的化合物，通过抑制CAG中的细胞凋亡和肠化生来调节JAK2/STAT3信号通路。 D PMID
  • 优化的超声辅助提取PHYSOCHLAINA_PHYSALOIDES根部总黄酮对HeLa宫颈癌细胞显示出细胞毒性活性。 D PMID
  • 研究从Physochlainae根中鉴定出九种新的甾体皂苷，并发现infundilide A在细胞和小鼠模型中均显示出抗炎作用。 D PMID
  • 从Physoclamia physaloides（BPP）中分离出的n-丁醇提取物在大鼠胃损伤中通过调节PPAR/NF-κB信号通路显示出保护作用。 D PMID

Frequently asked questions

What is Physochlaina?

Physochlaina (Physochlaina) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Physochlaina?

4 sourced findings are recorded for Physochlaina; the strongest carries evidence grade D. For example: 物理霍醇D，来自P. physaloides的化合物，通过抑制CAG中的细胞凋亡和肠化生来调节JAK2/STAT3信号通路。

How strong is the evidence for Physochlaina?

The strongest finding for Physochlaina carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Physochlaina safe? What are the side effects?

No major safety issues are recorded for Physochlaina in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Physochlaina interact with medications?

No drug interactions are recorded for Physochlaina in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Physochlaina?

Physochlaina is also known as: Пузырница.

Is Physochlaina a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Revealing the gastric protective mechanism of Physochlaina physaloides (L) G. Don. with clinical orientation: PPAR/NF-κB signalling pathway activation. literature abstract metadata
  2. T2 New steroidal saponins from Physochlainae Radix: Structures and anti-inflammatory efficacy. literature abstract metadata
  3. T2 Integrating network pharmacology, pharmacokinetics and experimental validation to reveal the potential mechanism of Physochlaina physaloides (L.) G. Don in chronic atrophic gastritis. literature abstract metadata
  4. T2 Optimized ultrasound extraction and cytotoxic activity against HeLa cervical cancer cells of total flavonoids of Physochlaina physaloides (L.) G. Don. literature abstract metadata