FolkKB

Physochlaina

Physochlaina

Physochlaina，一种传统上没有记录用途的植物，在现代科学研究中显示出潜力。研究表明其根部是针对宫颈癌HeLa细胞的细胞毒性活性来源，并且调节JAK2/STAT3途径以减轻慢性萎缩性胃炎。此外，从Physochlaina physaloides中分离出了九种新的甾体皂苷，其中infundilide A在细胞和小鼠模型中显示出显著的抗炎作用。Physochlaina physaloides的n-丁醇分数还显示了对大鼠胃损伤的保护作用，通过调节PPAR/NF-κB信号通路。目前的安全性问题较小，但需要进一步研究来确认这些发现。目前没有报告药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 物理霍醇D，来自P. physaloides的化合物，通过抑制CAG中的细胞凋亡和肠化生来调节JAK2/STAT3信号通路。 D PMID
  • 优化的超声辅助提取PHYSOCHLAINA_PHYSALOIDES根部总黄酮对HeLa宫颈癌细胞显示出细胞毒性活性。 D PMID
  • 研究从Physochlainae根中鉴定出九种新的甾体皂苷，并发现infundilide A在细胞和小鼠模型中均显示出抗炎作用。 D PMID
  • 从Physoclamia physaloides（BPP）中分离出的n-丁醇提取物在大鼠胃损伤中通过调节PPAR/NF-κB信号通路显示出保护作用。 D PMID

Frequently asked questions

What is Physochlaina?

Physochlaina (Physochlaina) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Physochlaina?

4 sourced findings are recorded for Physochlaina; the strongest carries evidence grade D. For example: 物理霍醇D，来自P. physaloides的化合物，通过抑制CAG中的细胞凋亡和肠化生来调节JAK2/STAT3信号通路。

How strong is the evidence for Physochlaina?

The strongest finding for Physochlaina carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Physochlaina safe? What are the side effects?

No major safety issues are recorded for Physochlaina in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Physochlaina interact with medications?

No drug interactions are recorded for Physochlaina in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Physochlaina?

Physochlaina is also known as: Пузырница.

Is Physochlaina a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Revealing the gastric protective mechanism of Physochlaina physaloides (L) G. Don. with clinical orientation: PPAR/NF-κB signalling pathway activation. literature abstract metadata
  2. T2 New steroidal saponins from Physochlainae Radix: Structures and anti-inflammatory efficacy. literature abstract metadata
  3. T2 Integrating network pharmacology, pharmacokinetics and experimental validation to reveal the potential mechanism of Physochlaina physaloides (L.) G. Don in chronic atrophic gastritis. literature abstract metadata
  4. T2 Optimized ultrasound extraction and cytotoxic activity against HeLa cervical cancer cells of total flavonoids of Physochlaina physaloides (L.) G. Don. literature abstract metadata