FolkKB

Picrorrhiza

Picrorhiza kurroa

Picrorhiza kurroa，传统上在阿育吠陀医学中使用，是一种原产于喜马拉雅地区的植物。它被用于其声称的健康益处，尽管具体的传统用途没有很好地记录下来。科学证据表明，Picrorhiza kurroa 可能具有潜在的心脏保护作用，如通过暴露于心脏应激源（如 ISO 和 DOX）的斑马鱼模型所观察到的那样，这表明其参与了多个生物途径。该综述强调了这种植物中存在多种治疗性植物分子的存在，其中一些作用仍然未被探索。个体提取物显示出比配方本身更强的抗炎效果，而从 Picrorhiza kurroa 提取的 Androsin 在结肠癌细胞上表现出抗增殖和促凋亡效应，并抑制了小鼠研究中的肿瘤生长。尚未发现这种植物存在重大安全问题或记录在案的药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 该回顾强调了来自Picrorhiza kurroa的重要药用植物分子，其中一些作用尚待进一步探索。 D PMID
  • Picrorhiza kurroa 和其他植物单体提取物在AYUSH-64中的抗炎作用强于其配方本身。 D PMID
  • BP1 治疗在ISO和DOX引起的心脏损伤的斑马鱼模型中显示出心脏保护作用，涉及多个途径。 D PMID
  • 从Picrorhiza kurroa中提取的Androsin通过不同的信号通路在低浓度和高浓度下抑制结肠癌细胞的增殖和侵袭。 D PMID

Frequently asked questions

What is Picrorrhiza?

Picrorrhiza (Picrorhiza kurroa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Picrorrhiza?

4 sourced findings are recorded for Picrorrhiza; the strongest carries evidence grade D. For example: 该回顾强调了来自Picrorhiza kurroa的重要药用植物分子，其中一些作用尚待进一步探索。

How strong is the evidence for Picrorrhiza?

The strongest finding for Picrorrhiza carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Picrorrhiza safe? What are the side effects?

No major safety issues are recorded for Picrorrhiza in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Picrorrhiza interact with medications?

No drug interactions are recorded for Picrorrhiza in our sources. This does not rule them out — check with a pharmacist.

Is Picrorrhiza a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Journey from phytomolecules to bioactive molecules: a phytopharmacological exploration of botanicals and standardised extract of Picrorhiza kurroa. literature abstract metadata
  2. T2 Androsin alleviates colorectal cancer by inhibiting the PI3K/Akt-centered signaling pathway. literature abstract metadata
  3. T2 Individual Botanicals Perform Better than AYUSH-64 Formulation in Suppressing TLR4-Driven Inflammatory Cytokines. literature abstract metadata
  4. T2 Multiomics Analysis Reveals the Protective Effect of a Novel Bioactive Peptide (BP1) in Cardiomyopathy Using a Zebrafish Model. literature abstract metadata