Polygonatum kingianum
Polygonatum kingianum
Polygonatum kingianum, a traditional medicine plant, is primarily associated with East Asian herbal practices. While its specific uses are not documented in historical or traditional contexts, studies have shown that its polysaccharides and saponins may improve cognitive functions in zebrafish, indicating potential neuroprotective benefits. Scientific evidence also suggests that the pathogen Aw causes root rot in Polygonatum kingianum, with Penicillium crustosum being another identified causal agent. Research has highlighted multi-target mechanisms involving EGFR, PI3K, HSP90AA1, SRC, and STAT3 pathways for potential treatment of Alzheimer's disease, though these findings are preliminary and need further validation in human studies. Notably, no major safety issues or drug interactions have been recorded for Polygonatum kingianum to date.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- PK多糖和皂苷均能改善斑马鱼的认知功能，但其神经保护作用谱不同。
- 研究确定了硒生物强化Polygonatum kingianum在涉及EGFR、PI3K、HSP90AA1、SRC和STAT3的阿尔茨海默病途径中的潜在多靶点机制。
- 研究确定Penicillium crustosum是Polygonatum kingianum根腐病的致病因素。
- 导致Polygonatum kingianum根腐病的主要病原体被鉴定为Aspergillus awamori，它上调了与木质素、黄酮类和植物-病原体相互作用途径相关的植物防御基因。
- 推测的二倍体和四倍体Polygonatum kingianum的线粒体基因组显示出结构差异，包括染色体数目和基因拷贝数的变化。
Frequently asked questions
What is Polygonatum kingianum?
Polygonatum kingianum (Polygonatum kingianum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Polygonatum kingianum?
5 sourced findings are recorded for Polygonatum kingianum; the strongest carries evidence grade D. For example: PK多糖和皂苷均能改善斑马鱼的认知功能，但其神经保护作用谱不同。
How strong is the evidence for Polygonatum kingianum?
The strongest finding for Polygonatum kingianum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Polygonatum kingianum safe? What are the side effects?
No major safety issues are recorded for Polygonatum kingianum in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Polygonatum kingianum interact with medications?
No drug interactions are recorded for Polygonatum kingianum in our sources. This does not rule them out — check with a pharmacist.
Is Polygonatum kingianum a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Exploring the Mechanism of Selenium-Biofortified Polygonatum Kingianum in Alzheimer's Disease: An Integrated Metabolomics and Network Pharmacology In Silico Study. literature abstract metadata
- T2 Identification of Root Rot Pathogens, Biological Control, and the Mechanism Analysis Underlying Polygonatum kingianum Response to Pathogen Stress. literature abstract metadata
- T2 Comprehensive analyses of different putative ploidy levels in organelle genomes of an important medicinal plant Polygonatum kingianum Collett & Hemsl. literature abstract metadata
- T2 The Effect of Polysaccharides and Saponins from Polygonatum kingianum on Cognitive Dysfunction in an AlCl3-Induced Alzheimer's Disease Zebrafish Model. literature abstract metadata
- T2 First Report and Biological Characterization of Penicillium crustosum Causing Root Rot in Polygonatum kingianum (Yunnan, China). literature abstract metadata