FolkKB

Premna obtusifolia

Premna obtusifolia

Premna obtusifolia 是一种传统上在各种民间医学实践中使用的植物，尽管其具体的传统应用尚未得到充分记录。现代药理学研究证实了 Premna integrifolia（可能与 P. obtusifolia 密切相关或相同）的一些民族医药主张，但活性成分及其生物作用仍需进一步验证。一项研究确定了 Taxodium ascendens 中 7β-羟基罗莱烯酮的晶体结构，尽管其绝对立体化学无法确定；相比之下，Premna obtusifolia 标题化合物的绝对构型被发现为 4bS、8aS 和 10R。值得注意的是，从 Premna obtusifolia 提取的 7-乙酰羟基激素明酮对人类结肠癌细胞系显示出强大的细胞毒性效果，但这一发现更广泛的含义仍需进一步探索。迄今为止尚未记录有关 Premna obtusifolia 的重大安全问题或药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 许多关于Premna integrifolia的民族医学主张已通过现代药理学研究得到证实，但活性成分和生物学作用仍需进一步验证。 D PMID
  • 已确定来自Taxodium ascendens的7β-羟基罗伊酮的晶体结构，但其绝对立体化学无法被最终确立。 D PMID
  • Premna obtusifolia 标题化合物的绝对构型确定为 4bS、8aS 和 10R。 D PMID
  • 研究发现，从Premna obtusifolia中提取的7-乙酰hornimone对人类结肠癌细胞系显示出强大的细胞毒性功效。 D PMID
  • Premna obtusifolia 和 Premna latifolia 均在大鼠中显示出抗炎潜力，其中Premna latifolia 更为有效。 D PMID

Frequently asked questions

What is Premna obtusifolia?

Premna obtusifolia (Premna obtusifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Premna obtusifolia?

5 sourced findings are recorded for Premna obtusifolia; the strongest carries evidence grade D. For example: 许多关于Premna integrifolia的民族医学主张已通过现代药理学研究得到证实，但活性成分和生物学作用仍需进一步验证。

How strong is the evidence for Premna obtusifolia?

The strongest finding for Premna obtusifolia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Premna obtusifolia safe? What are the side effects?

No major safety issues are recorded for Premna obtusifolia in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Premna obtusifolia interact with medications?

No drug interactions are recorded for Premna obtusifolia in our sources. This does not rule them out — check with a pharmacist.

Is Premna obtusifolia a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Redetermination and absolute configuration of 7α-hy-droxy-royleanone. literature abstract metadata
  2. T2 A comparative experimental evaluation of anti-inflammatory activity of Premna obtusifolia Linn and Premna latifolia Roxb leaves in Charles foster rats. literature abstract metadata
  3. T2 Pharmacological potentials of Premna integrifolia L. literature abstract metadata
  4. T2 Crystal structure of 7β-hy-droxy-royleanone isolated from Taxodium ascendens (B.). literature abstract metadata
  5. T2 Inhibition of Human Colorectal Cancer by a Natural Product 7-Acetylhorminone and Interactions with BSA/HSA: Multispectral Analysis and In Silico and In Vitro Studies. literature abstract metadata