FolkKB

Premna obtusifolia

Premna obtusifolia

Premna obtusifolia 是一种传统上在东南亚发现的植物，并被各种土著社区用于未明确的目的，尽管具体的传统用途尚未记录。初步科学研究表明，从 Premna integrifolia（可能包括 Premna obtusifolia）中提取的一些化合物具有潜在的抗炎作用，并显示出作为治疗结直肠癌的前景通过体外实验。Premna obtusifolia 中某些化合物如 7-乙酰羟基酮的绝对构型已被确定，支持其传统用途。此外，Premna obtusifolia 和 Premna latifolia 在小鼠中均表现出抗炎活性，其中 Premna latifolia 的效果更为显著。迄今为止尚未记录任何重大安全问题或药物相互作用与 Premna obtusifolia 相关。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 许多关于Premna integrifolia的民族医学主张已通过现代药理学研究得到证实，但活性成分和生物学作用仍需进一步验证。 D PMID
  • The crystal structure of 7β-hydroxy-royleanone from Taxodium ascendens was determined, but the absolute stereochemistry could not be definitively established. D PMID
  • Premna obtusifolia 标题化合物的绝对构型确定为 4bS、8aS 和 10R。 D PMID
  • 研究发现，从Premna obtusifolia中提取的7-乙酰hornimone对人类结肠癌细胞系显示出强大的细胞毒性功效。 D PMID
  • Premna obtusifolia 和 Premna latifolia 均在大鼠中显示出抗炎潜力，其中Premna latifolia 更为有效。 D PMID

Frequently asked questions

What is Premna obtusifolia?

Premna obtusifolia (Premna obtusifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Premna obtusifolia?

5 sourced findings are recorded for Premna obtusifolia; the strongest carries evidence grade D. For example: 许多关于Premna integrifolia的民族医学主张已通过现代药理学研究得到证实，但活性成分和生物学作用仍需进一步验证。

How strong is the evidence for Premna obtusifolia?

The strongest finding for Premna obtusifolia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Premna obtusifolia safe? What are the side effects?

No major safety issues are recorded for Premna obtusifolia in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Premna obtusifolia interact with medications?

No drug interactions are recorded for Premna obtusifolia in our sources. This does not rule them out — check with a pharmacist.

Is Premna obtusifolia a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Redetermination and absolute configuration of 7α-hy-droxy-royleanone. literature abstract metadata
  2. T2 A comparative experimental evaluation of anti-inflammatory activity of Premna obtusifolia Linn and Premna latifolia Roxb leaves in Charles foster rats. literature abstract metadata
  3. T2 Pharmacological potentials of Premna integrifolia L. literature abstract metadata
  4. T2 Crystal structure of 7β-hy-droxy-royleanone isolated from Taxodium ascendens (B.). literature abstract metadata
  5. T2 Inhibition of Human Colorectal Cancer by a Natural Product 7-Acetylhorminone and Interactions with BSA/HSA: Multispectral Analysis and In Silico and In Vitro Studies. literature abstract metadata