False Larch
Pseudolarix
Pseudolarix is a coniferous tree native to East Asia. While traditional uses of Pseudolarix are not well-documented, scientific research has shown promising results. Studies indicate that pseudolarolide B from this plant enhances PP2A holoenzyme assembly and anti-inflammatory activity, suggesting potential benefits in inflammation-related conditions. Additionally, pseudolaric acid B induces ferroptosis in lung cancer cells and causes G2/M phase arrest in canine mammary tumor cells, hinting at possible anticancer properties. Notably, Pseudolarix kaempferi extract improved symptoms of non-alcoholic fatty liver disease by modulating gut microbiota and increasing tryptophan metabolites that activate AhR to reduce hepatic lipogenesis. Safety profiles for this plant are currently favorable with no major issues recorded; however, further research is needed to confirm these findings. There are no known drug interactions reported at present.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 伪龙胆酸B在犬乳腺肿瘤细胞中通过靶向CDK1诱导G2/M期阻滞。
- 伪龙胆酸B通过JNK/ERK介导的survivin上调诱导肺癌细胞铁死亡。
- 伪洛罗利德B以共价方式与PPP2R1A结合，增强PP2A全酶组装和抗炎活性。
- Pseudolaric 酸B（PAB）来自Pseudolarix kaempferi，通过调节肠道微生物群并增加色氨酸代谢产物cinabarinic 酸，激活AhR从而减少肝脏脂质合成，改善了高脂肪饮食诱导的MAFLD症状。
Frequently asked questions
What is False Larch?
False Larch (Pseudolarix) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about False Larch?
4 sourced findings are recorded for False Larch; the strongest carries evidence grade D. For example: 伪龙胆酸B在犬乳腺肿瘤细胞中通过靶向CDK1诱导G2/M期阻滞。
How strong is the evidence for False Larch?
The strongest finding for False Larch carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is False Larch safe? What are the side effects?
No major safety issues are recorded for False Larch in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does False Larch interact with medications?
No drug interactions are recorded for False Larch in our sources. This does not rule them out — check with a pharmacist.
What are the common names of False Larch?
False Larch is also known as: Лжелиственница, Mélèze doré de Chine.
Is False Larch a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Gut microbiota-based metabolism contributes to the protection of pseudolaric acid B against MAFLD. literature abstract metadata
- T2 Pseudolaric acid B induces G2/M phase arrest in canine mammary tumor cells by targeting CDK1. literature abstract metadata
- T2 Pseudolaric acid B promotes lung cancer cells ferroptosis depending on JNK/ERK-mediated upregulation of survivin. literature abstract metadata
- T2 Covalent targeting of PP2A scaffold subunit PPP2R1A by Pseudolarolide B enhances holoenzyme assembly to exert anti-inflammatory activity. literature abstract metadata