Mélèze doré de Chine
Pseudolarix · False Larch
Pseudolarix is a coniferous tree native to East Asia. While traditional uses of Pseudolarix are not well-documented, scientific research has shown promising results. Studies indicate that pseudolarolide B from this plant enhances PP2A holoenzyme assembly and anti-inflammatory activity, suggesting potential benefits in inflammation-related conditions. Additionally, pseudolaric acid B induces ferroptosis in lung cancer cells and causes G2/M phase arrest in canine mammary tumor cells, hinting at possible anticancer properties. Notably, Pseudolarix kaempferi extract improved symptoms of non-alcoholic fatty liver disease by modulating gut microbiota and increasing tryptophan metabolites that activate AhR to reduce hepatic lipogenesis. Safety profiles for this plant are currently favorable with no major issues recorded; however, further research is needed to confirm these findings. There are no known drug interactions reported at present.
- Meilleure preuve
- D
- Précautions
- —
Information uniquement. L'usage traditionnel ne signifie pas une efficacité prouvée. Les preuves et la sécurité varient — consultez les sources citées.
Ce que dit la science
- L'acide pseudolarique B a provoqué une arrestation à la phase G2/M des cellules du tumour mammaire canin par ciblage de CDK1.
- L'acide pseudolarique B induit la ferropthose dans les cellules du cancer des poumons par l'intermédiaire d'une régulation de survivin via JNK/ERK.
- Le pseudolarolide B se lie covalentement à PPP2R1A, améliorant l'assemblage de l'holoenzym PP2A et l'activité antiréaction inflammatoire.
- L'acide pseudolarique B (PAB) provenant de Pseudolarix kaempferi a amélioré les symptômes du MAFLD induit par une alimentation riche en graisses, en modulant la microflore intestinale et en augmentant le métabolite de triptophane acide cinabrinique, ce qui a activé AhR pour réduire la lipogénèse hépatique.
Frequently asked questions
What is Mélèze doré de Chine?
Mélèze doré de Chine (Pseudolarix) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Mélèze doré de Chine?
4 sourced findings are recorded for Mélèze doré de Chine; the strongest carries evidence grade D. For example: L'acide pseudolarique B a provoqué une arrestation à la phase G2/M des cellules du tumour mammaire canin par ciblage de CDK1.
How strong is the evidence for Mélèze doré de Chine?
The strongest finding for Mélèze doré de Chine carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Mélèze doré de Chine safe? What are the side effects?
No major safety issues are recorded for Mélèze doré de Chine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Mélèze doré de Chine interact with medications?
No drug interactions are recorded for Mélèze doré de Chine in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Mélèze doré de Chine?
Mélèze doré de Chine is also known as: False Larch, Лжелиственница.
Is Mélèze doré de Chine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Gut microbiota-based metabolism contributes to the protection of pseudolaric acid B against MAFLD. literature abstract metadata
- T2 Pseudolaric acid B induces G2/M phase arrest in canine mammary tumor cells by targeting CDK1. literature abstract metadata
- T2 Pseudolaric acid B promotes lung cancer cells ferroptosis depending on JNK/ERK-mediated upregulation of survivin. literature abstract metadata
- T2 Covalent targeting of PP2A scaffold subunit PPP2R1A by Pseudolarolide B enhances holoenzyme assembly to exert anti-inflammatory activity. literature abstract metadata