FolkKB

Pterocephalus hookeri

Pterocephalus hookeri

Pterocephalus hookeri 是一种传统上未被充分记录用于药用的植物。科学研究已从该植物中鉴定出九种新的伊里多酮，其中一种在某些人类癌细胞系中表现出适度的细胞毒活性。该研究还开发了一种方法，用于测定 Pterocephali Herba 中 18 种生物活性成分，表明样品质量存在变异。Pterocephalus hookeri 展示了抗炎、镇痛、抗癌和神经保护作用；然而，体内药代动力学研究有限。值得注意的是，pterocephin A 在给药后 72 小时内在多种组织中被检测到，其中最高浓度出现在肝脏。 目前尚未广泛报道关于 Pterocephalus hookeri 的安全性问题，也没有记录到显著的药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 从Pterocephalus hookeri中鉴定出九种新的异环二萜，其中一种对三种人类癌细胞系表现出中等的细胞毒性。 D PMID
  • 该研究开发了一种同时定量分析pterocephali草中18个生物活性成分的方法，揭示了样品之间的质量不一致。 D PMID
  • pterocephalus hookeri 展现了抗炎、镇痛、抗癌和神经保护作用，但对其体内药代动力学的研究有限。 D PMID
  • 在给药后72小时内，检测到了pterocephin A在多种组织中存在，并且肝中的浓度最高。 D PMID
  • 在Pterocephalus hookeri地上部分和地下部分之间鉴定了差异代谢物，指导临床用药。 D PMID

Frequently asked questions

What is Pterocephalus hookeri?

Pterocephalus hookeri (Pterocephalus hookeri) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Pterocephalus hookeri?

5 sourced findings are recorded for Pterocephalus hookeri; the strongest carries evidence grade D. For example: 从Pterocephalus hookeri中鉴定出九种新的异环二萜，其中一种对三种人类癌细胞系表现出中等的细胞毒性。

How strong is the evidence for Pterocephalus hookeri?

The strongest finding for Pterocephalus hookeri carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Pterocephalus hookeri safe? What are the side effects?

No major safety issues are recorded for Pterocephalus hookeri in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Pterocephalus hookeri interact with medications?

No drug interactions are recorded for Pterocephalus hookeri in our sources. This does not rule them out — check with a pharmacist.

Is Pterocephalus hookeri a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Traditional uses, phytochemistry, pharmacology, and toxicology of Pterocephalus hookeri (C. B. Clarke) Höeck: a review. literature abstract metadata
  2. T2 Quality evaluation of Pterocephali Herba through simultaneously quantifying 18 bioactive components by UPLC-TQ-MS/MS analysis. literature abstract metadata
  3. T2 Ptehosides A-I: Nine undescribed iridoids with in vitro cytotoxicity from the whole plant of Pterocephalus hookeri (C.B. Clarke) Höeck. literature abstract metadata
  4. T2 Toxicokinetics and Tissue Distribution of the Hepatotoxic Triterpenoid Saponin Pterocephin A in Rats Using the Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) Method. literature abstract metadata
  5. T2 Chemical Profiling of Aboveground and Underground Parts of Pterocephalus hookeri by Integrated FBMN, Untargeted LC-MS Metabolomics, and PAD-DESI-MSI. literature abstract metadata