Pterocephalus hookeri
Pterocephalus hookeri
Pterocephalus hookeri is a plant traditionally used in few documented practices. Scientific studies have identified nine new iridoids from this plant, with one showing moderate cytotoxic activity against certain human cancer cell lines. The plant has shown anti-inflammatory, analgesic, anticancer, and neuroprotective activities; however, in vivo pharmacokinetic studies are limited. Pterocephalin A was detected in various tissues up to 72 hours after administration, with the highest concentrations found in the liver. No significant safety concerns or recorded drug interactions have been noted for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Nine new iridoids were identified from Pterocephalus hookeri, with one exhibiting moderate cytotoxic activity against three human cancer cell lines.
- The study developed a method to simultaneously quantify 18 bioactive components in Pterocephali Herba, revealing inconsistent quality among samples.
- Pterocephalus hookeri exhibits anti-inflammatory, analgesic, anticancer, and neuroprotective activities, but studies on its in vivo pharmacokinetics are limited.
- Pterocephin A was detected in various tissues up to 72 hours after administration, with highest concentrations in the liver.
- Differential metabolites were identified between aboveground and underground parts of Pterocephalus hookeri, guiding clinical medication.
Frequently asked questions
What is Pterocephalus hookeri?
Pterocephalus hookeri (Pterocephalus hookeri) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pterocephalus hookeri?
5 sourced findings are recorded for Pterocephalus hookeri; the strongest carries evidence grade D. For example: Nine new iridoids were identified from Pterocephalus hookeri, with one exhibiting moderate cytotoxic activity against three human cancer cell lines.
How strong is the evidence for Pterocephalus hookeri?
The strongest finding for Pterocephalus hookeri carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pterocephalus hookeri safe? What are the side effects?
No major safety issues are recorded for Pterocephalus hookeri in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pterocephalus hookeri interact with medications?
No drug interactions are recorded for Pterocephalus hookeri in our sources. This does not rule them out — check with a pharmacist.
Is Pterocephalus hookeri a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Traditional uses, phytochemistry, pharmacology, and toxicology of Pterocephalus hookeri (C. B. Clarke) Höeck: a review. literature abstract metadata
- T2 Quality evaluation of Pterocephali Herba through simultaneously quantifying 18 bioactive components by UPLC-TQ-MS/MS analysis. literature abstract metadata
- T2 Ptehosides A-I: Nine undescribed iridoids with in vitro cytotoxicity from the whole plant of Pterocephalus hookeri (C.B. Clarke) Höeck. literature abstract metadata
- T2 Toxicokinetics and Tissue Distribution of the Hepatotoxic Triterpenoid Saponin Pterocephin A in Rats Using the Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) Method. literature abstract metadata
- T2 Chemical Profiling of Aboveground and Underground Parts of Pterocephalus hookeri by Integrated FBMN, Untargeted LC-MS Metabolomics, and PAD-DESI-MSI. literature abstract metadata