Devil's-Pepper
Rauvolfia
Rauvolia 是一种传统上在各种形式的传统医学中使用的植物属，特别是在印度草药学和非洲传统实践中。Rauvolia serpentina 的种子因其潜在的抗铜绿假单胞菌活性而闻名，因为它们干扰了 P. aeruginosa 中的群体感应和生物膜形成，一项研究还确定了参与次级代谢物生物合成和根部发育的关键基因。同样，在西非传统医学中使用的十二种抗糖尿病植物之一 Rauvolia vomitoria 由于其降血糖活性而受到注意，尽管需要进一步的科学验证。科学研究表明有前景的生物学活动但仍然有限。没有记录到主要的安全问题或药物相互作用，这表明该植物总体上是安全的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从雷公藤种子提取物在通过干扰铜绿假单胞菌的群体感应和生物被膜形成显示出了抗铜绿假单胞菌活性。
- 研究鉴定出关键基因，包括STR1、ABI3/VP1和WRKY25，参与雷公藤属植物Rauvolfia serpentina次生代谢物生物合成及根系发育。
- 研究阐明了RsSTR催化1-IEA与secologanin反应形成罕见的哌嗪吲哚骨架的机制细节。
- 这项研究在十二种常用于西非传统医学的抗糖尿病植物中鉴定出了Rauvolfia vomitoria，显示出显著的降血糖活性，但需要进一步的科学验证。
Frequently asked questions
What is Devil's-Pepper?
Devil's-Pepper (Rauvolfia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Devil's-Pepper?
4 sourced findings are recorded for Devil's-Pepper; the strongest carries evidence grade D. For example: 从雷公藤种子提取物在通过干扰铜绿假单胞菌的群体感应和生物被膜形成显示出了抗铜绿假单胞菌活性。
How strong is the evidence for Devil's-Pepper?
The strongest finding for Devil's-Pepper carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Devil's-Pepper safe? What are the side effects?
No major safety issues are recorded for Devil's-Pepper in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Devil's-Pepper interact with medications?
No drug interactions are recorded for Devil's-Pepper in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Devil's-Pepper?
Devil's-Pepper is also known as: Раувольфия.
Is Devil's-Pepper a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Comparative transcriptome analysis reveals ABI3/VP1-WRKY25-STR1 regulatory module linking specialized metabolism with root system development and stress response in Rauvolfia serpentina. literature abstract metadata
- T2 Diabetes mellitus in ECOWAS: an overview of the safety and efficacy of medicinal plants used in traditional medicine practices. literature abstract metadata
- T2 Disruption in Quorum-Sensing Circuits and Biofilm Matrix in Pseudomonas aeruginosa by Super-Critical CO2 Extracted Oleoresins From Rauvolfia serpentina Seeds Rescue Caenorhabditis elegans Model of Infection. literature abstract metadata
- T2 Mechanistic elucidation of strictosidine synthase-catalyzed Pictet-Spengler reaction for rare piperazine-indole scaffold formation. literature abstract metadata