FolkKB

Siler

Saposhnikovia divaricata

Saposhnikovia divaricata，传统中医中通常称为防风，传统上用于其假设的抗炎和免疫调节作用。然而，并没有记录特定的传统用途。科学证据表明，在某些条件下，Saposhnikovia divaricata 可能会促进植物生长并改变根际微生物群。此外，含 Saposhnikovia divaricata 的 Yupingfeng San 方剂的提取物在肾间质纤维化模型中显示出肾脏保护作用。另外，从 Saposhnikovia divaricata 中衍生出的化合物，如 CHR 和 Prim-O-葡萄糖基西蒙芬，可能通过特定途径调节免疫细胞极化并缓解类风湿性关节炎。迄今为止，并未报告该植物存在重大安全问题或药物相互作用。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 来自Saposhnikovia divaricata的CHR调节M1巨噬细胞极化并改善RA，通过靶向CBLL1，尽管确切机制仍部分未明。 D PMID
  • 用Aspergillus neoalliaceus MR-86接种后，Saposhnikovia divaricata的生长增加，并改变了其根际微生物群。 D PMID
  • 玉屏风散提取物在顺铂诱导的肾间质纤维化中通过调节IL-6/JAK/STAT3途径和线粒体稳态显示出肾保护作用。 D PMID
  • 来自Saposhnikovia divaricata的Prim-O-葡萄糖基西夫鲁苷通过靶向GBP5减轻类风湿性关节炎，抑制焦亡并抑制滑膜细胞增殖。 D PMID

Frequently asked questions

What is Siler?

Siler (Saposhnikovia divaricata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Siler?

4 sourced findings are recorded for Siler; the strongest carries evidence grade D. For example: 来自Saposhnikovia divaricata的CHR调节M1巨噬细胞极化并改善RA，通过靶向CBLL1，尽管确切机制仍部分未明。

How strong is the evidence for Siler?

The strongest finding for Siler carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Siler safe? What are the side effects?

No major safety issues are recorded for Siler in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Siler interact with medications?

No drug interactions are recorded for Siler in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Siler?

Siler is also known as: Сапожниковия растопыренная.

Is Siler a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Chromones from Saposhnikovia divaricata modulate m6A RNA methylation-mediated macrophage polarization by targeting CBLL1 to ameliorate RA. literature abstract metadata
  2. T2 Yupingfeng San extract ameliorates cisplatin induced renal interstitial fibrosis via IL-6/JAK/STAT3 mediated restoration of mitochondrial homeostasis. literature abstract metadata
  3. T2 Prim-O-glucosylcimifugin ameliorates rheumatoid arthritis by targeting GBP5 to suppress pyroptosis and inhibit synovial cell proliferation. literature abstract metadata
  4. T2 Aspergillus neoalliaceus MR-86 Promotes the Growth of Saposhnikovia divaricata by Regulating the Rhizosphere Microbiome. literature abstract metadata