FolkKB

Siler

Saposhnikovia divaricata

独活（Saposhnikovia divaricata）是一种植物，目前未见有传统用途的记载。一些初步的科学研究表明，其提取物可能调节M1巨噬细胞极化，并通过靶向CBLL1或GBP5来抑制细胞凋亡，从而可能改善类风湿性关节炎，但确切的机制仍有待进一步阐明。此外，鱼腥草颗粒提取物在某些模型中显示出对顺铂诱导的肾间质纤维化的潜在肾保护作用。现有数据中未记录到重大的安全性问题或显著的药物相互作用。本信息仅供教育目的。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 来自Saposhnikovia divaricata的CHR调节M1巨噬细胞极化并改善RA，通过靶向CBLL1，尽管确切机制仍部分未明。 D PMID
  • 用Aspergillus neoalliaceus MR-86接种后，Saposhnikovia divaricata的生长增加，并改变了其根际微生物群。 D PMID
  • 玉屏风散提取物在顺铂诱导的肾间质纤维化中通过调节IL-6/JAK/STAT3途径和线粒体稳态显示出肾保护作用。 D PMID
  • 来自Saposhnikovia divaricata的Prim-O-葡萄糖基西夫鲁苷通过靶向GBP5减轻类风湿性关节炎，抑制焦亡并抑制滑膜细胞增殖。 D PMID

Frequently asked questions

What is Siler?

Siler (Saposhnikovia divaricata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Siler?

4 sourced findings are recorded for Siler; the strongest carries evidence grade D. For example: 来自Saposhnikovia divaricata的CHR调节M1巨噬细胞极化并改善RA，通过靶向CBLL1，尽管确切机制仍部分未明。

How strong is the evidence for Siler?

The strongest finding for Siler carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Siler safe? What are the side effects?

No major safety issues are recorded for Siler in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Siler interact with medications?

No drug interactions are recorded for Siler in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Siler?

Siler is also known as: Сапожниковия растопыренная.

Is Siler a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Chromones from Saposhnikovia divaricata modulate m6A RNA methylation-mediated macrophage polarization by targeting CBLL1 to ameliorate RA. literature abstract metadata
  2. T2 Yupingfeng San extract ameliorates cisplatin induced renal interstitial fibrosis via IL-6/JAK/STAT3 mediated restoration of mitochondrial homeostasis. literature abstract metadata
  3. T2 Prim-O-glucosylcimifugin ameliorates rheumatoid arthritis by targeting GBP5 to suppress pyroptosis and inhibit synovial cell proliferation. literature abstract metadata
  4. T2 Aspergillus neoalliaceus MR-86 Promotes the Growth of Saposhnikovia divaricata by Regulating the Rhizosphere Microbiome. literature abstract metadata