FolkKB

Glabrous Sarcandra Herb

Sarcandra glabra

sarcantra glabra 是一种传统上在中国医学中使用的植物，但该物种的具体传统用途尚未见文献记载。科学证据表明，其多糖可能具有免疫调节、抗炎和抗氧化作用，潜在地通过抑制P2X7/PSME3驱动的20S蛋白酶体过度激活来缓解慢性肾病。sarcantra glabra中的总黄酮也显示出对K562细胞存活率有显著抑制作用，并通过影响鞘脂代谢和PI3K/Akt信号通路的抑制促进凋亡，表明可能具有抗癌特性。从sarcantra glabra中分离出的四sarcantragltones A和B表现出对癌细胞的细胞毒性活性，通过抑制NF-κB途径来抑制癌细胞。迄今为止尚未发现sarcantra glabra的主要安全问题或药物相互作用。

速览
最佳证据
A
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • TSA通过抑制P2X7/PSME3介导的20S蛋白酶体超激活来缓解慢性肾病。 D PMID
  • 该综述综合了S. glabra多糖的药理学证据，将传统用途与现代关于免疫调节、抗炎和抗氧化活性的研究结果联系起来。 A PMID
  • 从山茶属植物 sarcandra glabra 提取的总黄酮显著抑制了 k562 细胞活力并促进了凋亡，通过影响鞘脂代谢和抑制 pi3k/akt 信号通路。 D PMID
  • Tetrasargltones A 和 B，来源于 Sarcandra glabra，显示出对癌细胞系的细胞毒活性，其中一种化合物抑制 NF‑κB 通路。 D PMID

Frequently asked questions

What is Glabrous Sarcandra Herb?

Glabrous Sarcandra Herb (Sarcandra glabra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Glabrous Sarcandra Herb?

4 sourced findings are recorded for Glabrous Sarcandra Herb; the strongest carries evidence grade A. For example: TSA通过抑制P2X7/PSME3介导的20S蛋白酶体超激活来缓解慢性肾病。

How strong is the evidence for Glabrous Sarcandra Herb?

The strongest finding for Glabrous Sarcandra Herb carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Glabrous Sarcandra Herb safe? What are the side effects?

No major safety issues are recorded for Glabrous Sarcandra Herb in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Glabrous Sarcandra Herb interact with medications?

No drug interactions are recorded for Glabrous Sarcandra Herb in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Glabrous Sarcandra Herb?

Glabrous Sarcandra Herb is also known as: Саркандра голая.

Is Glabrous Sarcandra Herb a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 A review of Sarcandra glabra (Thunb.) Nakai polysaccharides: Extraction, structural characteristics, pharmacology, and structure-activity relationships. literature abstract metadata
  2. T2 [Total flavonoids from Sarcandra glabra promote apoptosis in leukemia K562 cells via sphingolipid metabolism and PI3K/Akt signaling pathway based on cellular metabolomics]. literature abstract metadata
  3. T2 Trishizukaol A alleviates chronic kidney disease by restraining P2X7/PSME3-driven 20S proteasome hyperactivation. literature abstract metadata
  4. T2 Tetrasargltones A and B, Fully Helically Polymerized Lindenane Sesquiterpenoid Tetramers from Sarcandra glabra. literature abstract metadata