Chinese figwort

Scrophularia ningpoensis

Scrophularia ningpoensis,一种传统的中国药用植物,在东亚草药实践中主要被使用。尽管其具体用途在历史上记载不多,但研究表明它在多个研究领域显示出有希望的结果。科学研究表明,这种植物中的harpagoside可能通过减少一氧化氮的生成和抑制α-突触核蛋白硝化而提供细胞保护作用,这可能对神经退行性疾病有益。此外,包裹在Scrophularia ningpoensis多糖熊去氧胆酸纳米颗粒中的bufalin显示出比游离bufalin更强的抗肝肿瘤活性,表明其可能具有对抗肝癌的治疗应用潜力。Angoroside C的干预改善了糖尿病小鼠的葡萄糖和脂质代谢、胰岛素抵抗以及组织病理学异常,暗示可能对代谢性疾病有益。Qishen软膏通过上调心肌驻留巨噬细胞中的Cx43而改善心力衰竭小鼠的心脏功能和传导,表明潜在的心血管益处。迄今为止尚未发现主要的安全问题或记录到的药物相互作用。

速览
最佳证据
D
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 羟基喜树碱在罗tenone处理的N2A细胞中表现出显著的细胞保护作用,通过抑制NO生成和α-突触核蛋白硝化。 D PMID
  • The study found that bufalin encapsulated in Scrophularia ningpoensis polysaccharide-ursodeoxycholic acid nanoparticles showed enhanced anti-liver tumor activity compared to free bufalin. D PMID
  • angoroside C 干预以剂量依赖性方式改善了 db/db 小鼠的葡萄糖和脂质代谢、胰岛素抵抗以及组织病理学异常。 D PMID
  • Qishen软膏通过上调心肌驻留巨噬细胞中的Cx43表达,改善了心力衰竭小鼠的心脏功能和传导。 D PMID
  • HPG通过调节肠道微生物群以增加乙酸的产生来缓解由败血症引起的ARDS,从而激活FFAR2并重新编程免疫反应。 D PMID

Frequently asked questions

What is Chinese figwort?

Chinese figwort (Scrophularia ningpoensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Chinese figwort?

5 sourced findings are recorded for Chinese figwort; the strongest carries evidence grade D. For example: 羟基喜树碱在罗tenone处理的N2A细胞中表现出显著的细胞保护作用,通过抑制NO生成和α-突触核蛋白硝化。

How strong is the evidence for Chinese figwort?

The strongest finding for Chinese figwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Chinese figwort safe? What are the side effects?

No major safety issues are recorded for Chinese figwort in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Chinese figwort interact with medications?

No drug interactions are recorded for Chinese figwort in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Chinese figwort?

Chinese figwort is also known as: Норичник нингпонский.

Is Chinese figwort a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Angoroside C: A potent AMPK activator in the aqueous extract of Scrophularia ningpoensis, alleviates metabolic syndrome in db/db mice. literature abstract metadata
  2. T2 [Preparation, characterization, and in vitro anti-liver tumor activity of bufalin nanoparticles with Scrophularia ningpoensis polysaccharide and ursodeoxycholic acid as carriers]. literature abstract metadata
  3. T2 Reduced levels of nitrated α-synuclein in the protective effect of harpagoside on rotenone-induced cellular models of Parkinson's disease. literature abstract metadata
  4. T2 Harpagide alleviates sepsis-induced acute respiratory distress syndrome via gut microbiota modulation. literature abstract metadata
  5. T2 Qishen Paste Improves Cardiac Conduction in Heart Failure by Regulating Cardiac Resident Macrophage Connexin43. literature abstract metadata