Chinese figwort
Scrophularia ningpoensis
Scrophularia ningpoensis，一种传统的中国药用植物，在各种草药疗法中被使用了几个世纪。虽然具体的传统用途没有很好地记录下来，但它经常被包含在用于治疗肝脏疾病和心血管问题的配方中。 科学证据表明，Scrophularia ningpoensis中的化合物，特别是哈帕戈斯苷，可能通过减少一氧化氮生成并抑制α-突触核蛋白硝化对神经元具有细胞保护作用。此外，从这种植物衍生的聚糖-熊去氧胆酸纳米颗粒包封的 bufalin 显示出增强的抗肿瘤活性对抗肝癌细胞。Angoroside C 干预措施在糖尿病小鼠中显示出葡萄糖和脂质代谢、胰岛素抵抗和组织病理学异常的改善。此外，用 Scrophularia ningpoensis 制备的 Qishen 膏剂已被观察到通过上调心肌驻留巨噬细胞中的 connexin 43 (Cx43) 表达来改善心力衰竭小鼠的心脏功能和传导。 尚未报告有关 Scrophularia ningpoensis 的重大安全问题或药物相互作用，但进一步的研究对于完全了解其潜在益处和风险是必要的。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 羟基喜树碱在罗tenone处理的N2A细胞中表现出显著的细胞保护作用，通过抑制NO生成和α-突触核蛋白硝化。
- 研究发现，bufalin被包裹在Scrophularia ningpoensis polysaccharide-ursodeoxycholic acid nanoparticles中，其抗肝瘤活性优于自由bufalin。
- angoroside C 干预以剂量依赖性方式改善了 db/db 小鼠的葡萄糖和脂质代谢、胰岛素抵抗以及组织病理学异常。
- Qishen软膏通过上调心肌驻留巨噬细胞中的Cx43表达，改善了心力衰竭小鼠的心脏功能和传导。
- HPG通过调节肠道微生物群以增加乙酸的产生来缓解由败血症引起的ARDS，从而激活FFAR2并重新编程免疫反应。
Frequently asked questions
What is Chinese figwort?
Chinese figwort (Scrophularia ningpoensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese figwort?
5 sourced findings are recorded for Chinese figwort; the strongest carries evidence grade D. For example: 羟基喜树碱在罗tenone处理的N2A细胞中表现出显著的细胞保护作用，通过抑制NO生成和α-突触核蛋白硝化。
How strong is the evidence for Chinese figwort?
The strongest finding for Chinese figwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese figwort safe? What are the side effects?
No major safety issues are recorded for Chinese figwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese figwort interact with medications?
No drug interactions are recorded for Chinese figwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese figwort?
Chinese figwort is also known as: Норичник нингпонский.
Is Chinese figwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Angoroside C: A potent AMPK activator in the aqueous extract of Scrophularia ningpoensis, alleviates metabolic syndrome in db/db mice. literature abstract metadata
- T2 [Preparation, characterization, and in vitro anti-liver tumor activity of bufalin nanoparticles with Scrophularia ningpoensis polysaccharide and ursodeoxycholic acid as carriers]. literature abstract metadata
- T2 Reduced levels of nitrated α-synuclein in the protective effect of harpagoside on rotenone-induced cellular models of Parkinson's disease. literature abstract metadata
- T2 Harpagide alleviates sepsis-induced acute respiratory distress syndrome via gut microbiota modulation. literature abstract metadata
- T2 Qishen Paste Improves Cardiac Conduction in Heart Failure by Regulating Cardiac Resident Macrophage Connexin43. literature abstract metadata