Buerger’s figwort
Scrophularia buergeriana
Scrophularia buergeriana，一种原产于东亚的传统药用植物，在历史或文化医学实践中并未广泛记录。科学研究显示了有希望的结果，表明其可能对认知健康和大脑功能具有潜在益处。研究发现，该植物的提取物可以通过调节神经炎症并促进通过涉及小胶质细胞和神经元的信号通路进行神经保护来减轻由阿托品诱导的认知障碍在小鼠中的影响。此外，它还表现出类似雌激素的作用，如其能够促进MCF-7细胞增殖并增加ERα表达所证明的一样。尽管尚未报告重大安全问题或药物相互作用，但这些发现是初步的，需要进一步研究。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，Scrophularia buergeriana 提取物在减轻由 scopalamine 引起的小鼠认知障碍方面显示出潜力，并且在皮层和海马体中发现了代谢变化。
- 金铁锁提取物减少了神经炎症并促进了神经保护，通过调节小胶质细胞和神经元中的信号传导途径。
- Brainon® 的给药改善了SAMP8小鼠的认知缺陷并缓解了与AD相关的病理过程，但没有明确给出剂量或治疗建议。
- Scrophularia buergeriana 根提取物表现出类似雌激素的活性，通过促进MCF-7 细胞增殖和增加ERα 表达。
Frequently asked questions
What is Buerger’s figwort?
Buerger’s figwort (Scrophularia buergeriana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Buerger’s figwort?
4 sourced findings are recorded for Buerger’s figwort; the strongest carries evidence grade D. For example: 研究发现，Scrophularia buergeriana 提取物在减轻由 scopalamine 引起的小鼠认知障碍方面显示出潜力，并且在皮层和海马体中发现了代谢变化。
How strong is the evidence for Buerger’s figwort?
The strongest finding for Buerger’s figwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Buerger’s figwort safe? What are the side effects?
No major safety issues are recorded for Buerger’s figwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Buerger’s figwort interact with medications?
No drug interactions are recorded for Buerger’s figwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Buerger’s figwort?
Buerger’s figwort is also known as: Норичник Бюргера.
Is Buerger’s figwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Effects of Scrophularia buergeriana Extract (Brainon®) on Aging-Induced Memory Impairment in SAMP8 Mice. literature abstract metadata
- T2 Scrophularia buergeriana Extract (Brainon) Attenuates Neuroinflammation in BV-2 Microglia Cells and Promotes Neuroprotection in SH-SY5Y Neuroblastoma Cells. literature abstract metadata
- T2 Metabolomics study to reveal cognitive improvement with treatment of Scrophularia buergeriana. literature abstract metadata
- T2 Estrogen-like Activity of Scrophularia buergeriana Root Extracts in MCF-7 Cells. literature abstract metadata