Alexandrian senna

Senna alexandrina

番泻叶(又称亚历山大番泻或埃及番泻),是一种传统上与中东和北非地区相关的植物。它在传统医学中因其被认为具有缓泻作用而被使用,但具体的用途可能因文化实践的不同而异。科学研究表明,番泻叶提取物可以显著改变哈门尼线虫的能源代谢和氧化还原平衡,导致其死亡。此外,一项研究显示,含有番泻叶亚历山大的通泄方剂(Tongxie Yaofang)可减轻结肠炎症并增加小鼠患有肠易激综合症主导症状(IBS-D)时的肠道微生物多样性。含番泻叶提取物的草药缓泻胶囊配方在与安慰剂相比管理骨科患者术后便秘方面显示出显著疗效。目前,番泻叶亚历山大的安全概况没有显示重大问题,并且尚未记录与其使用相关的药物相互作用。然而,进一步的研究对于全面了解这种植物在各种背景下的潜在效果和相互作用是必要的。

速览
最佳证据
B
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • 番泻叶提取物显著改变哈门尼线虫Hymenolepis diminuta的能量代谢和氧化还原平衡,导致寄生虫死亡。 D PMID
  • 通泻药方减轻了结肠炎症并调节了IBS-D小鼠的肠道微生物群。 D PMID
  • 该研究开发了一管多色SCAR检测方法,用于精确鉴定S. alexandrina及其掺假物种。 D PMID
  • HLC制剂在缓解骨科手术后便秘方面与安慰剂相比显示出显著的有效性。 B PMID

Frequently asked questions

What is Alexandrian senna?

Alexandrian senna (Senna alexandrina) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Alexandrian senna?

4 sourced findings are recorded for Alexandrian senna; the strongest carries evidence grade B. For example: 番泻叶提取物显著改变哈门尼线虫Hymenolepis diminuta的能量代谢和氧化还原平衡,导致寄生虫死亡。

How strong is the evidence for Alexandrian senna?

The strongest finding for Alexandrian senna carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Alexandrian senna safe? What are the side effects?

No major safety issues are recorded for Alexandrian senna in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Alexandrian senna interact with medications?

No drug interactions are recorded for Alexandrian senna in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Alexandrian senna?

Alexandrian senna is also known as: Сенна александрийская, Séné.

Is Alexandrian senna a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Efficacy of an Iranian herbal medicine formula for postoperative constipation in trauma patients with hip and lower limb fractures: A triple-blind, placebo-controlled randomized clinical trial. literature abstract metadata
  2. T2 Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing. literature abstract metadata
  3. T2 Exploring Metabolic Disruption and Redox Modulation by Senna Leaf Extracts Induces Mortality in the Zoonotic Parasite Hymenolepis diminuta. literature abstract metadata
  4. T2 Development of One-Tube Multiplex Arbitrary (RAPD and ISSR) Marker-Based SCAR Assay for Simultaneous Detection and Authentication of Indian Senna (Senna alexandrina Mill.) and Its Adulterant Species. literature abstract metadata