Alexandrian senna
Senna alexandrina
番泻叶（Senna alexandrina），又称亚历山大番泻叶或埃及番泻叶，是一种传统植物，在草药医学中主要被使用。它因其泻下作用和治疗便秘而被传统上使用，但具体用途可能因不同文化而异。科学证据表明，番泻叶提取物可以引起胡敏线虫（Hymenolepis diminuta）能量代谢和氧化还原平衡的显著变化，导致其死亡，暗示潜在的抗寄生虫作用。此外，一种含有S. alexandrina的传统中药“通泻药方”在缓解肠炎并调节小鼠肠道微生物群方面显示出对主导症状为肠易激综合症（IBS-D）的小鼠的有效性。为了精确鉴定番泻叶及其掺假物种，开发了一种单管多重SCAR测定法，从而提高了其使用准确性。HLC配方在与安慰剂相比的骨科患者中管理术后便秘方面显示出显著效果。没有记录到主要的安全问题或药物相互作用，但需要进一步的研究来全面确认这些发现。
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 番泻叶提取物显著改变哈门尼线虫Hymenolepis diminuta的能量代谢和氧化还原平衡，导致寄生虫死亡。
- 通泻药方减轻了结肠炎症并调节了IBS-D小鼠的肠道微生物群。
- 该研究开发了一管多色SCAR检测方法，用于精确鉴定S. alexandrina及其掺假物种。
- HLC制剂在缓解骨科手术后便秘方面与安慰剂相比显示出显著的有效性。
Frequently asked questions
What is Alexandrian senna?
Alexandrian senna (Senna alexandrina) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Alexandrian senna?
4 sourced findings are recorded for Alexandrian senna; the strongest carries evidence grade B. For example: 番泻叶提取物显著改变哈门尼线虫Hymenolepis diminuta的能量代谢和氧化还原平衡，导致寄生虫死亡。
How strong is the evidence for Alexandrian senna?
The strongest finding for Alexandrian senna carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Alexandrian senna safe? What are the side effects?
No major safety issues are recorded for Alexandrian senna in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Alexandrian senna interact with medications?
No drug interactions are recorded for Alexandrian senna in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Alexandrian senna?
Alexandrian senna is also known as: Сенна александрийская, Séné.
Is Alexandrian senna a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Efficacy of an Iranian herbal medicine formula for postoperative constipation in trauma patients with hip and lower limb fractures: A triple-blind, placebo-controlled randomized clinical trial. literature abstract metadata
- T2 Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing. literature abstract metadata
- T2 Exploring Metabolic Disruption and Redox Modulation by Senna Leaf Extracts Induces Mortality in the Zoonotic Parasite Hymenolepis diminuta. literature abstract metadata
- T2 Development of One-Tube Multiplex Arbitrary (RAPD and ISSR) Marker-Based SCAR Assay for Simultaneous Detection and Authentication of Indian Senna (Senna alexandrina Mill.) and Its Adulterant Species. literature abstract metadata