American Sicklepod
Senna obtusifolia
番泻叶，一种传统药用植物，在北非和亚洲部分地区发现，尚未广泛记录其特定的传统用途。然而，它在实验室研究中显示出抗真菌和杀虫的潜力，并与其他审查过的植物一起。科学证据表明，它可能通过调节与骨关节炎（OA）和肝纤维化相关的信号通路而具有潜在益处，OBT治疗有望减轻CCl4诱导的肝纤维化，影响ROCK2/Cofilin-1/NFκB途径。此外，在急性胰腺炎模型中观察到，用obtusifolin治疗可减少炎症和组织损伤，通过调节NFκB信号通路。安全性数据显示没有重大问题，并且目前没有报告与番泻叶相关的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- Obtusifolin 治疗减少了体外和体内急性胰腺炎模型中的炎症和组织损伤，通过调节NFκB信号传导。
- 在其他审查的植物中，Senna obtusifolia 在实验室条件下显示出抗真菌和杀虫作用。
- 圣吉塞分析识别出与OA相关的关键信号通路，这些通路可能通过从番泻叶（Senna obtusifolia）中提取的天然提取物进行调节。
- OBT 治疗通过调节 ROCK2/Cofilin-1/NFκB 路径在体外和体内模型中减轻了四氯化碳诱导的肝纤维化。
- 番泻叶（Senna obtusifolia）摄入导致山羊肌肉无力和肌纤维退化，进而引发肌病。
Frequently asked questions
What is American Sicklepod?
American Sicklepod (Senna obtusifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about American Sicklepod?
5 sourced findings are recorded for American Sicklepod; the strongest carries evidence grade D. For example: Obtusifolin 治疗减少了体外和体内急性胰腺炎模型中的炎症和组织损伤，通过调节NFκB信号传导。
How strong is the evidence for American Sicklepod?
The strongest finding for American Sicklepod carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is American Sicklepod safe? What are the side effects?
No major safety issues are recorded for American Sicklepod in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does American Sicklepod interact with medications?
No drug interactions are recorded for American Sicklepod in our sources. This does not rule them out — check with a pharmacist.
What are the common names of American Sicklepod?
American Sicklepod is also known as: Casse fétide.
Is American Sicklepod a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Toxic myopathy in dairy goats caused by spontaneous ingestion of Senna obtusifolia. literature abstract metadata
- T2 Obtusifolin mitigates CCl4-induced inflammation and liver fibrosis by modulating the ROCK2/ Cofilin-1 / NFκB pathway. literature abstract metadata
- T2 Obtusifolin ameliorates pancreatic tissue injury and inflammation by modulating the NFκB signaling. literature abstract metadata
- T2 SaintGSE: Transformer-based efficient and explainable gene set enrichment analysis. literature abstract metadata
- T2 Medicinal Plants as Biopesticides Against Pests and Diseases of Maize (Zea mays L.) in Africa: Ethnobotanical Insights and Challenges. literature abstract metadata