Trigonostemon
Trigonostemon
Trigonostemon is a plant with traditional medicine roots, though specific uses are not documented. Scientific research has shown that Trigonochinene E from this plant promotes lysosomal biogenesis and autophagy in human degenerative nucleus pulposus cells, indicating potential benefits for conditions involving cell degradation. Extracts from Trigonostemon xyphophyllorides have also demonstrated significant anti-proliferative effects on renal cancer cells through the PI3K/AKT pathway, suggesting possible applications in oncology. Additionally, compounds strophiofimbrin A and B showed notable proliferation inhibition and neuroprotective effects, while PSO exhibited antiproliferative activity against renal cell carcinoma cells by inhibiting the PI3K/AKT pathway. To date, no major safety issues or drug interactions have been recorded for Trigonostemon, but further research is needed to fully understand its potential benefits and risks.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究发现，Trigonostemon xyphophyllorides 提取物在通过 PI3K-AKT 路径对肾癌细胞表现出显著的抗增殖作用。
- 三叶苦参烯E促进溶酶体生物发生并经由TFEB/TFE3增强自噬作用于人类退行性NP细胞。
- 从Strophioblachia fimbricalyx中鉴定出两种新的重新排列的诺尔二萜，具有独特的三环结构，显示出一定的增殖抑制和神经保护活性。
- PSO，三角叶千斤拔的有效成分，在抑制PI3K/AKT途径活性的同时，对肾细胞癌细胞显示出了强大的抗增殖作用。
- 描述了从Trigonostemon xyphophylloides合成了K和L两种三甲氧菲。
Frequently asked questions
What is Trigonostemon?
Trigonostemon (Trigonostemon) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Trigonostemon?
5 sourced findings are recorded for Trigonostemon; the strongest carries evidence grade D. For example: 研究发现，Trigonostemon xyphophyllorides 提取物在通过 PI3K-AKT 路径对肾癌细胞表现出显著的抗增殖作用。
How strong is the evidence for Trigonostemon?
The strongest finding for Trigonostemon carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Trigonostemon safe? What are the side effects?
No major safety issues are recorded for Trigonostemon in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Trigonostemon interact with medications?
No drug interactions are recorded for Trigonostemon in our sources. This does not rule them out — check with a pharmacist.
Is Trigonostemon a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress. literature abstract metadata
- T2 Strophiofimbrins A and B: Two Rearranged Norditerpenoids with Novel Tricyclic Carbon Skeletons from Strophioblachia fimbricalyx. literature abstract metadata
- T2 Two Total Syntheses of Trigoxyphins K and L. literature abstract metadata
- T2 Antiproliferative effects of Trigonostemon xyphophyllorides on renal cell carcinoma via the PI3K/AKT pathway. literature abstract metadata
- T2 Multi-omics analysis reveals psoralen to suppresses renal cell carcinoma through the PI3K/AKT pathway. literature abstract metadata