FolkKB

Trigonostemon

Trigonostemon

Trigonostemon 是一种植物属，传统医学主要源于东南亚地区，尽管这些植物的具体用途尚未详细记录。科学研究表明，从 Trigonostemon xyphophyllorides 提取的提取物在 PI3K-AKT 路径上对肾癌细胞表现出显著的抗增殖作用。此外，Strophioblachia fimbricalyx 中的 Trigonochinene E 通过 TFEB/TFE3 在退行性 NP 细胞中促进溶酶体生物发生并增强自噬。从该属鉴定出的两种新的重排 norditerpenoids 显示出一些增殖抑制和神经保护活性。活性成分 PSO 还通过抑制 PI3K/AKT 路径在肾细胞癌细胞中表现出强大的抗增殖作用。迄今为止，这些化合物未记录任何重大安全问题或药物相互作用，但进一步研究对于完全了解其潜在益处和风险是必要的。

速览
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

科学怎么说

  • 研究发现，Trigonostemon xyphophyllorides 提取物在通过 PI3K-AKT 路径对肾癌细胞表现出显著的抗增殖作用。 D PMID
  • 三叶苦参烯E促进溶酶体生物发生并经由TFEB/TFE3增强自噬作用于人类退行性NP细胞。 D PMID
  • 从Strophioblachia fimbricalyx中鉴定出两种新的重新排列的诺尔二萜，具有独特的三环结构，显示出一定的增殖抑制和神经保护活性。 D PMID
  • PSO，三角叶千斤拔的有效成分，在抑制PI3K/AKT途径活性的同时，对肾细胞癌细胞显示出了强大的抗增殖作用。 D PMID
  • 描述了从Trigonostemon xyphophylloides合成了K和L两种三甲氧菲。 D PMID

Frequently asked questions

What is Trigonostemon?

Trigonostemon (Trigonostemon) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Trigonostemon?

5 sourced findings are recorded for Trigonostemon; the strongest carries evidence grade D. For example: 研究发现，Trigonostemon xyphophyllorides 提取物在通过 PI3K-AKT 路径对肾癌细胞表现出显著的抗增殖作用。

How strong is the evidence for Trigonostemon?

The strongest finding for Trigonostemon carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Trigonostemon safe? What are the side effects?

No major safety issues are recorded for Trigonostemon in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Trigonostemon interact with medications?

No drug interactions are recorded for Trigonostemon in our sources. This does not rule them out — check with a pharmacist.

Is Trigonostemon a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress. literature abstract metadata
  2. T2 Strophiofimbrins A and B: Two Rearranged Norditerpenoids with Novel Tricyclic Carbon Skeletons from Strophioblachia fimbricalyx. literature abstract metadata
  3. T2 Two Total Syntheses of Trigoxyphins K and L. literature abstract metadata
  4. T2 Antiproliferative effects of Trigonostemon xyphophyllorides on renal cell carcinoma via the PI3K/AKT pathway. literature abstract metadata
  5. T2 Multi-omics analysis reveals psoralen to suppresses renal cell carcinoma through the PI3K/AKT pathway. literature abstract metadata