Thunder God Vine
Tripterygium wilfordii
三叶鬼臼（又称雷神藤）是一种传统草药，在中医中被广泛使用。其传统用途包括治疗类风湿性关节炎和其他自身免疫性疾病，但具体应用在不同实践者之间差异很大。研究表明，从三叶鬼臼中提取的三甲基氧化物，当与伊立替康联合使用时，可能具有抗癌活性，并且在体外和体内均显示出对结肠癌细胞的增强作用。此外，该草药与紫镇藤茎的组合比单独使用这些草药更能显著降低炎症标志物并改善关节功能。还观察到其潜在的抗病毒效果以及通过抑制CD33机制对抗阿尔茨海默病相关神经炎症的好处。尚未记录重大安全问题或药物相互作用，但进一步研究对于完全了解其治疗应用和可能的副作用是必要的。
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 伊立替康和三七脂酸酯的联合使用在体外和体内的人结肠癌细胞中增强了抗癌活性，通过增加凋亡作用。
- 三叶鬼臼和_sinomenium茎与传统中药递送药物结合使用，在减少炎症标志物和改善关节功能方面比单独使用草药效果更显著。
- 本研究回顾了三七皂苷的传统用途及其化学特征，突出了具有潜在抗病毒作用的萜类化合物。
- 从Tripterygium wilfordii中分离出八种新的化合物，在细胞模型中表现出一定的抗炎活性。
- 三甲基异黄酮可减少胆固醇合成并缓解阿尔茨海默病中的神经炎症，可能通过CD33/SHP-1/JAK1/STAT6途径实现。
- 紫檀醇通过TLR4/STAT3/NLRP3途径调节，减少了小鼠和巨噬细胞中的炎症性坏死（pyroptosis），从而抑制了动脉粥样硬化。
Frequently asked questions
What is Thunder God Vine?
Thunder God Vine (Tripterygium wilfordii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Thunder God Vine?
6 sourced findings are recorded for Thunder God Vine; the strongest carries evidence grade B. For example: 伊立替康和三七脂酸酯的联合使用在体外和体内的人结肠癌细胞中增强了抗癌活性，通过增加凋亡作用。
How strong is the evidence for Thunder God Vine?
The strongest finding for Thunder God Vine carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Thunder God Vine safe? What are the side effects?
No major safety issues are recorded for Thunder God Vine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Thunder God Vine interact with medications?
No drug interactions are recorded for Thunder God Vine in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Thunder God Vine?
Thunder God Vine is also known as: Триптеригиум Вильфорда.
Is Thunder God Vine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Influence of Tripterygium wilfordii Hook F and Caulis Sinomenii with traditional Chinese medicine directed drug delivery on CD3+, CD4+, CD8+ and joint function in rheumatoid arthritis patients. literature abstract metadata
- T2 Triptolide enhances anti-cancer activities of irinotecan in human colon cancer HT-29 cells in vitro and HT-29 cell xenograft tumor model in nude mice. literature abstract metadata
- T2 Celastrol ameliorates atherosclerosis by inhibiting TLR4/STAT3/NLRP3-mediated macrophage pyroptosis. literature abstract metadata
- T2 Anti-inflammatory sesquiterpenes and diterpenes from Tripterygium wilfordii Hook. f. literature abstract metadata
- T2 Taming the thunder god vine: Antiviral terpenoids from Tripterygium wilfordii. literature abstract metadata
- T2 Triptolide Reduces Cholesterol Synthesis and Alleviates Neuroinflammation by Inhibiting CD33 in Alzheimer's Disease Development and Progression. literature abstract metadata