Thunder God Vine
Tripterygium wilfordii
三叶鬼臼，又称雷神藤，是一种传统中药植物。它被用于各种民间疗法中，但这种植物的具体传统用途尚未有很好的记录。科学证据表明，当与伊立替康联合使用时，它可以增强抗癌活性，并且与其他传统中药一起使用时可以改善关节功能和炎症标志物。在阿尔茨海默病模型中，三叶鬼臼中的关键成分雷公藤内酯通过CD33/SHP-1/JAK1/STAT6途径显示出降低胆固醇水平并减轻神经炎症的潜力。然而，这些证据仍然有限且范围较小。这种植物没有记录到显著的安全问题或药物相互作用，但需要进一步研究以全面了解其潜在应用和作用机制。
- 最佳证据
- B
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 伊立替康和三七脂酸酯的联合使用在体外和体内的人结肠癌细胞中增强了抗癌活性，通过增加凋亡作用。
- 三叶鬼臼和_sinomenium茎与传统中药递送药物结合使用，在减少炎症标志物和改善关节功能方面比单独使用草药效果更显著。
- 本研究回顾了三七皂苷的传统用途及其化学特征，突出了具有潜在抗病毒作用的萜类化合物。
- Eight new compounds were isolated from Tripterygium wilfordii, showing some anti-inflammatory activity in cell models.
- 三甲基异黄酮可减少胆固醇合成并缓解阿尔茨海默病中的神经炎症，可能通过CD33/SHP-1/JAK1/STAT6途径实现。
- 紫檀醇通过TLR4/STAT3/NLRP3途径调节，减少了小鼠和巨噬细胞中的炎症性坏死（pyroptosis），从而抑制了动脉粥样硬化。
Frequently asked questions
What is Thunder God Vine?
Thunder God Vine (Tripterygium wilfordii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Thunder God Vine?
6 sourced findings are recorded for Thunder God Vine; the strongest carries evidence grade B. For example: 伊立替康和三七脂酸酯的联合使用在体外和体内的人结肠癌细胞中增强了抗癌活性，通过增加凋亡作用。
How strong is the evidence for Thunder God Vine?
The strongest finding for Thunder God Vine carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Thunder God Vine safe? What are the side effects?
No major safety issues are recorded for Thunder God Vine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Thunder God Vine interact with medications?
No drug interactions are recorded for Thunder God Vine in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Thunder God Vine?
Thunder God Vine is also known as: Триптеригиум Вильфорда.
Is Thunder God Vine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Influence of Tripterygium wilfordii Hook F and Caulis Sinomenii with traditional Chinese medicine directed drug delivery on CD3+, CD4+, CD8+ and joint function in rheumatoid arthritis patients. literature abstract metadata
- T2 Triptolide enhances anti-cancer activities of irinotecan in human colon cancer HT-29 cells in vitro and HT-29 cell xenograft tumor model in nude mice. literature abstract metadata
- T2 Celastrol ameliorates atherosclerosis by inhibiting TLR4/STAT3/NLRP3-mediated macrophage pyroptosis. literature abstract metadata
- T2 Anti-inflammatory sesquiterpenes and diterpenes from Tripterygium wilfordii Hook. f. literature abstract metadata
- T2 Taming the thunder god vine: Antiviral terpenoids from Tripterygium wilfordii. literature abstract metadata
- T2 Triptolide Reduces Cholesterol Synthesis and Alleviates Neuroinflammation by Inhibiting CD33 in Alzheimer's Disease Development and Progression. literature abstract metadata