Regel’s threewingnut
Tripterygium regelii
三叶鬼臼（Tripterygium regelii）原产于中国和其他亚洲地区，传统上未用于医疗用途。最近的科学研究显示了令人鼓舞的结果；其树皮提取物在SARS-CoV 3CLpro上的IC50值为2.6 ± 0.6 μmol L-1，表明可能具有抗病毒活性。此外，从三叶鬼臼根部鉴定出的萜类化合物显示出对结肠癌的潜在抑制作用，通过诱导一种新化合物中的铁死亡。来自同一植物根部的成分7和13表现出显著的抗炎活性，通过激活AHR并抑制多个信号通路。值得注意的是，在森林空地发现三叶鬼臼侵入后，A. nephrolepis 的死亡可能会影响树木再生。目前尚未报告安全问题，迄今为止未记录任何重大问题。到目前为止，没有与三叶鬼臼相关的药物相互作用被记录。
- 最佳证据
- A
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从Tripterygium regelii树皮中提取的物质对SARS-CoV 3CLpro表现出强大的抑制活性，IC50为2.6±0.6μmol/L。
- 研究在Tripterygium regelii根中鉴定出了萜类化合物，其中一个新化合物通过诱导铁死亡显示出潜在的抗结肠直肠癌功效。
- 来自三叶鬼臼根的化合物7和13显示出显著的抗炎活性，通过激活AHR并抑制多个信号传导途径。
- 在林冠空隙中观察到Tripterygium regelii入侵，这可能阻碍树苗的再生。
Frequently asked questions
What is Regel’s threewingnut?
Regel’s threewingnut (Tripterygium regelii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Regel’s threewingnut?
4 sourced findings are recorded for Regel’s threewingnut; the strongest carries evidence grade A. For example: 从Tripterygium regelii树皮中提取的物质对SARS-CoV 3CLpro表现出强大的抑制活性，IC50为2.6±0.6μmol/L。
How strong is the evidence for Regel’s threewingnut?
The strongest finding for Regel’s threewingnut carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Regel’s threewingnut safe? What are the side effects?
No major safety issues are recorded for Regel’s threewingnut in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Regel’s threewingnut interact with medications?
No drug interactions are recorded for Regel’s threewingnut in our sources. This does not rule them out — check with a pharmacist.
Is Regel’s threewingnut a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Medicinal plants with anti-SARS-CoV activity repurposing for treatment of COVID-19 infection: A systematic review and meta-analysis. literature abstract metadata
- T2 Pre-drought effects on northern temperate trees and vine invasion in forest gaps hindering regeneration. literature abstract metadata
- T2 Macrolide sesquiterpene pyridine alkaloids from the roots of Tripterygium regelii and their anti-inflammatory activity. literature abstract metadata
- T2 Diterpenoids and triterpenoids from the roots of Tripterygium regelii and their inhibitory effects on colorectal cancer cells. literature abstract metadata