small-fruit wild frangipani
Voacanga africana
非洲瓦卡纳是一种传统植物，主要与西非草药医学传统相关，但其具体用途尚未充分记录。科学研究揭示了其根皮中存在多种生物碱，包括voacandial和voacanginone A，这些物质最近被分离出来。Voagafries B 和 E 对 SH-SY5Y 细胞显示出显著的细胞毒性作用，而从该植物中分离出的七种生物碱表现出抗疟疾活性，IC50 值在 5.734 ± 1.365 至 5.319 ± 2.206 µg/mL 范围内，分别对应 voacamine (2) 和 voacorine (3)。然而，当前的科学证据有限，需要更多的研究来全面了解其潜在的医学应用。迄今为止尚未发现主要的安全问题或药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 从 Voacanga africana 提取的 voacamine（2）和 voacorine（3）碱性化合物在体外显示出良好的抗疟疾活性，IC50 值分别为 5.734 ± 1.365 和 5.319 ± 2.206 µg/mL。
- 从Voacanga africana中分离出七种生物碱，其中两种能够抑制大肠杆菌生物膜。
- 来自非洲漆树的Voagafries B和E对SH-SY5Y细胞显示出显著的细胞毒性。
- 从Voacanga africana树皮中分离出了两种新的iboga型单萜吲哚生物碱，voacandial和voacanginone A。
Frequently asked questions
What is small-fruit wild frangipani?
small-fruit wild frangipani (Voacanga africana) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about small-fruit wild frangipani?
4 sourced findings are recorded for small-fruit wild frangipani; the strongest carries evidence grade D. For example: 从 Voacanga africana 提取的 voacamine（2）和 voacorine（3）碱性化合物在体外显示出良好的抗疟疾活性，IC50 值分别为 5.734 ± 1.365 和 5.319 ± 2.206 µg/mL。
How strong is the evidence for small-fruit wild frangipani?
The strongest finding for small-fruit wild frangipani carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is small-fruit wild frangipani safe? What are the side effects?
No major safety issues are recorded for small-fruit wild frangipani in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does small-fruit wild frangipani interact with medications?
No drug interactions are recorded for small-fruit wild frangipani in our sources. This does not rule them out — check with a pharmacist.
What are the common names of small-fruit wild frangipani?
small-fruit wild frangipani is also known as: Воаканга африканская, voacanga d'Afrique.
Is small-fruit wild frangipani a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Spirooxindol alkaloids from Voacanga africana: Targeting biofilm of MBLs producing Escherichia coli. literature abstract metadata
- T2 Voagafries A-E, undescribed indole alkaloids with anti-glioma activity from Voacanga africana. literature abstract metadata
- T2 Voacandial and Voacanginone A, Iboga-Type Monoterpenoid Indole Alkaloids from Voacanga africana Root Bark: Isolation, Structure Elucidation, and Asymmetric Total Syntheses. literature abstract metadata
- T2 Iboga-Indole Alkaloids as Potential Plasmodial Inhibitors: Identification, Biosynthesis, and Molecular Docking Studies. literature abstract metadata