East African Green Wood
Warburgia salutaris
Warburgia salutaris 是一种传统上在某些非洲和东南亚文化中使用的植物，尽管其具体的传统用途尚未广泛记录。科学研究表明，其叶子的非包封提取物和脂质体提取物均表现出浓度依赖性的细胞毒性对抗乳腺癌细胞，机制不同于氯喹。研究还发现 Iso-mukaadial 酯上调与寄生虫生物学过程及细胞黏附相关的基因表达，突显了多种潜在的治疗应用。尽管 Warburgia salutaris 叶片中的新转录组数据与挥发性精油成分相关，并且已识别出萜类生物合成的联系，但目前尚未发现该植物存在显著的安全问题或记录的药物相互作用。
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 无论是未包封还是脂质体包裹的Warburgia salutaris叶提取物，均表现出浓度依赖性的细胞毒性作用，并且具有不同的机制。
- 研究发现，来自瓦尔布里亚·萨利达里斯的异-木卡迪醇醋酸酯上调与寄生虫生物学过程和细胞黏附相关的基因表达，其机制不同于氯喹。
- 这项研究将新生成的转录组数据与W. salutaris叶中挥发油成分相关联，识别出萜类生物合成基因之间的联系。
- Warburgia salutaris 叶提取物在MCF-7 细胞中表现出抗增殖作用，上调促凋亡蛋白和半胱天冬酶的表达。
Frequently asked questions
What is East African Green Wood?
East African Green Wood (Warburgia salutaris) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about East African Green Wood?
4 sourced findings are recorded for East African Green Wood; the strongest carries evidence grade D. For example: 无论是未包封还是脂质体包裹的Warburgia salutaris叶提取物，均表现出浓度依赖性的细胞毒性作用，并且具有不同的机制。
How strong is the evidence for East African Green Wood?
The strongest finding for East African Green Wood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is East African Green Wood safe? What are the side effects?
No major safety issues are recorded for East African Green Wood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does East African Green Wood interact with medications?
No drug interactions are recorded for East African Green Wood in our sources. This does not rule them out — check with a pharmacist.
Is East African Green Wood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 Identification of Bioactive Compounds in Warburgia salutaris Leaf Extracts and Their Pro-Apoptotic Effects on MCF-7 Breast Cancer Cells. literature abstract metadata
- T2 The impact of Iso-mukaadial acetate on Plasmodium falciparum transcriptional gene regulation. literature abstract metadata
- T2 Evaluation of the Anticancer Effects of Warburgia salutaris Leaf Extracts: A Comparative Study of Both Liposomal-Encapsulated and Unencapsulated Extracts, with Mechanistic Insights into Apoptotic Signalling. literature abstract metadata
- T2 Exploratory Correlation of De Novo Transcriptome Data and GC-MS Volatile Essential Oils Profile of W. salutaris Leaves. literature abstract metadata