East African Green Wood
Warburgia salutaris
Warburgia salutaris is a tree species rooted in African traditional medicine. It is traditionally used to address malaria, respiratory complaints, stomach-ache, constipation, coughs, fever, toothache, muscle pains, and weak joints. Some laboratory studies suggest that leaf extracts may exhibit concentration-dependent cytotoxicity against breast cancer cells and antiproliferative effects by upregulating pro-apoptotic proteins. Additionally, research indicates that iso-mukaadial acetate may influence genes related to parasite biological processes. No major safety issues or notable drug interactions have been recorded.
- Traditionally for
- malaria · respiratory complaints
- Traditions
- Western phytotherapy
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- malaria
- respiratory complaints
- stomach-ache
- constipation
- coughs
- fever
- toothache
- muscle pains
- weak joints
What the science says
- Both unencapsulated and liposomal Warburgia salutaris leaf extracts showed concentration-dependent cytotoxicity against breast cancer cells with different mechanisms.
- The study found that Iso-mukaadial acetate from Warburgia salutaris upregulated genes related to parasite biological processes and cell adhesion, differing in mechanisms from chloroquine.
- This study correlated de novo transcriptome data with volatile essential oil compounds in W. salutaris leaves, identifying links to terpene biosynthesis genes.
- Warburgia salutaris leaf extracts exhibited antiproliferative effects on MCF-7 cells, upregulating pro-apoptotic proteins and caspases.
Frequently asked questions
What is East African Green Wood?
East African Green Wood (Warburgia salutaris) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is East African Green Wood traditionally used for?
Traditional sources record East African Green Wood for: malaria, respiratory complaints, stomach-ache, constipation, coughs, fever. This reflects traditional use, not a proven medical treatment.
Which traditions use East African Green Wood?
East African Green Wood appears in these traditions in our sources: Western phytotherapy.
What does the scientific evidence say about East African Green Wood?
4 sourced findings are recorded for East African Green Wood; the strongest carries evidence grade D. For example: Both unencapsulated and liposomal Warburgia salutaris leaf extracts showed concentration-dependent cytotoxicity against breast cancer cells with different mechanisms.
How strong is the evidence for East African Green Wood?
The strongest finding for East African Green Wood carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is East African Green Wood safe? What are the side effects?
No major safety issues are recorded for East African Green Wood in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does East African Green Wood interact with medications?
No drug interactions are recorded for East African Green Wood in our sources. This does not rule them out — check with a pharmacist.
Is East African Green Wood a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Identification of Bioactive Compounds in Warburgia salutaris Leaf Extracts and Their Pro-Apoptotic Effects on MCF-7 Breast Cancer Cells. literature abstract metadata
- T2 The impact of Iso-mukaadial acetate on Plasmodium falciparum transcriptional gene regulation. literature abstract metadata
- T2 Evaluation of the Anticancer Effects of Warburgia salutaris Leaf Extracts: A Comparative Study of Both Liposomal-Encapsulated and Unencapsulated Extracts, with Mechanistic Insights into Apoptotic Signalling. literature abstract metadata
- T2 Exploratory Correlation of De Novo Transcriptome Data and GC-MS Volatile Essential Oils Profile of W. salutaris Leaves. literature abstract metadata
- T3 Warburgia salutaris CC BY-SA 4.0