Hairy agrimony

Agrimonia pilosa, also known as common agrimony or black cat's tail, is a traditional Chinese herb with roots in Eastern and Central Europe. Traditionally, it has not been extensively used for specific medicinal purposes across various cultures. Scientific evidence from human studies shows mixed results; while there were no significant changes observed in middle-aged individuals, Agrimonia pilosa demonstrated beneficial effects in animal models by reducing liver injury markers and improving metabolic dysfunction through lipid metabolism regulation and inflammation suppression. Additionally, it showed promise in mitigating myocardial injury and inhibiting excessive mitophagy via modulation of the FOXO signaling pathway in mice with isoproterenol-induced myocardial fibrosis. Variations in terpene synthase expression were noted to correlate with tissue-specific and seasonal terpene accumulation in Agrimonia pilosa, indicating potential adaptability and seasonality in its composition. Notably, no major safety concerns or drug interactions have been recorded for this plant.

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