Hairy agrimony
Agrimonia pilosa
Agrimonia pilosa, also known as common agrimony or black cat's tail, is a traditional Chinese herb with roots in Eastern and Central Europe. Traditionally, it has not been extensively used for specific medicinal purposes across various cultures. Scientific evidence from human studies shows mixed results; while there were no significant changes observed in middle-aged individuals, Agrimonia pilosa demonstrated beneficial effects in animal models by reducing liver injury markers and improving metabolic dysfunction through lipid metabolism regulation and inflammation suppression. Additionally, it showed promise in mitigating myocardial injury and inhibiting excessive mitophagy via modulation of the FOXO signaling pathway in mice with isoproterenol-induced myocardial fibrosis. Variations in terpene synthase expression were noted to correlate with tissue-specific and seasonal terpene accumulation in Agrimonia pilosa, indicating potential adaptability and seasonality in its composition. Notably, no major safety concerns or drug interactions have been recorded for this plant.
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Agrimonia pilosa reduced liver injury markers and improved metabolic dysfunction in mice by regulating lipid metabolism and suppressing inflammation.
- There were no statistically significant changes in the primary or secondary endpoints due to Agrimonia pilosa extract intake in middle-aged individuals.
- The study identified and characterized terpene synthases in Agrimonia pilosa, showing tissue-specific and seasonal variations in terpene accumulation.
- Agrimonia pilosa Ledeb. attenuated myocardial injury and inhibited excessive mitophagy through modulation of the FOXO signaling pathway in isoproterenol-induced myocardial fibrosis.
Frequently asked questions
What is Hairy agrimony?
Hairy agrimony (Agrimonia pilosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Hairy agrimony?
4 sourced findings are recorded for Hairy agrimony; the strongest carries evidence grade B. For example: Agrimonia pilosa reduced liver injury markers and improved metabolic dysfunction in mice by regulating lipid metabolism and suppressing inflammation.
How strong is the evidence for Hairy agrimony?
The strongest finding for Hairy agrimony carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Hairy agrimony safe? What are the side effects?
No major safety issues are recorded for Hairy agrimony in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Hairy agrimony interact with medications?
No drug interactions are recorded for Hairy agrimony in our sources. This does not rule them out — check with a pharmacist.
Is Hairy agrimony a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Preliminary Data on the Senolytic Effects of Agrimonia pilosa Ledeb. Extract Containing Agrimols for Immunosenescence in Middle-Aged Humans: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Study. literature abstract metadata
- T2 Multi-target protective effects of Agrimonia pilosa Ledeb. against metabolic dysfunction-associated steatohepatitis in mice. literature abstract metadata
- T2 Variations of terpenes profiling and functional characterization of terpene synthases in Agrimonia pilosa. literature abstract metadata
- T2 Protective Effects of Agrimonia pilosa Ledeb. In Myocardial Fibrosis: Inhibition of Mitophagy Mediated by the FOXO Signaling Pathway. literature abstract metadata