Hairy agrimony
Agrimonia pilosa
Agrimonia pilosa, a traditional Chinese herb also known as "stinking goat's-rue," has been studied for its potential health benefits. Traditionally, there are no specific records of its use in any particular medical traditions. Scientific evidence suggests that Agrimonia pilosa may have some beneficial effects; it reduced liver injury markers and improved metabolic dysfunction in mice by regulating lipid metabolism and suppressing inflammation. However, studies involving human middle-aged individuals did not show significant changes due to the intake of Agrimonia pilosa extract. Additionally, Agrimonia pilosa was found to attenuate myocardial injury and inhibit excessive mitophagy through modulation of the FOXO signaling pathway in isoproterenol-induced myocardial fibrosis. The study also identified and characterized terpene synthases in Agrimonia pilosa, showing tissue-specific and seasonal variations in terpene accumulation. No major safety issues or drug interactions have been recorded for this plant.
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Agrimonia pilosa reduced liver injury markers and improved metabolic dysfunction in mice by regulating lipid metabolism and suppressing inflammation.
- There were no statistically significant changes in the primary or secondary endpoints due to Agrimonia pilosa extract intake in middle-aged individuals.
- The study identified and characterized terpene synthases in Agrimonia pilosa, showing tissue-specific and seasonal variations in terpene accumulation.
- Agrimonia pilosa Ledeb. attenuated myocardial injury and inhibited excessive mitophagy through modulation of the FOXO signaling pathway in isoproterenol-induced myocardial fibrosis.
Frequently asked questions
What is Hairy agrimony?
Hairy agrimony (Agrimonia pilosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Hairy agrimony?
4 sourced findings are recorded for Hairy agrimony; the strongest carries evidence grade B. For example: Agrimonia pilosa reduced liver injury markers and improved metabolic dysfunction in mice by regulating lipid metabolism and suppressing inflammation.
How strong is the evidence for Hairy agrimony?
The strongest finding for Hairy agrimony carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Hairy agrimony safe? What are the side effects?
No major safety issues are recorded for Hairy agrimony in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Hairy agrimony interact with medications?
No drug interactions are recorded for Hairy agrimony in our sources. This does not rule them out — check with a pharmacist.
Is Hairy agrimony a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Preliminary Data on the Senolytic Effects of Agrimonia pilosa Ledeb. Extract Containing Agrimols for Immunosenescence in Middle-Aged Humans: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Study. literature abstract metadata
- T2 Multi-target protective effects of Agrimonia pilosa Ledeb. against metabolic dysfunction-associated steatohepatitis in mice. literature abstract metadata
- T2 Variations of terpenes profiling and functional characterization of terpene synthases in Agrimonia pilosa. literature abstract metadata
- T2 Protective Effects of Agrimonia pilosa Ledeb. In Myocardial Fibrosis: Inhibition of Mitophagy Mediated by the FOXO Signaling Pathway. literature abstract metadata