Hairy agrimony

Agrimonia pilosa

Agrimonia pilosa, also known as common agrimony or black cat's tail, is a traditional Chinese herb with roots in Eastern and Central Europe. Traditionally, it has not been extensively used for specific medicinal purposes across various cultures. Scientific evidence from human studies shows mixed results; while there were no significant changes observed in middle-aged individuals, Agrimonia pilosa demonstrated beneficial effects in animal models by reducing liver injury markers and improving metabolic dysfunction through lipid metabolism regulation and inflammation suppression. Additionally, it showed promise in mitigating myocardial injury and inhibiting excessive mitophagy via modulation of the FOXO signaling pathway in mice with isoproterenol-induced myocardial fibrosis. Variations in terpene synthase expression were noted to correlate with tissue-specific and seasonal terpene accumulation in Agrimonia pilosa, indicating potential adaptability and seasonality in its composition. Notably, no major safety concerns or drug interactions have been recorded for this plant.

速览
最佳证据
B
注意事项

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同,请查阅所引来源。

科学怎么说

  • Agrimonia pilosa 减少了小鼠肝损伤标志物并改善了代谢功能障碍,通过调节脂质代谢和抑制炎症。 D PMID
  • 在中年人群中,服用 Agrimonia pilosa 提取物后,主要或次要终点没有统计学上的显著变化。 B PMID
  • 研究识别并表征了Agrimonia pilosa中的萜类合成酶,显示出萜类积累具有组织特异性和季节性变化。 D PMID
  • Agrimonia pilosa Ledeb. 减轻心肌损伤并抑制异丙肾上腺素诱导的心肌纤维化中过度的自噬通过调节FOXO信号通路。 D PMID

Frequently asked questions

What is Hairy agrimony?

Hairy agrimony (Agrimonia pilosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Hairy agrimony?

4 sourced findings are recorded for Hairy agrimony; the strongest carries evidence grade B. For example: Agrimonia pilosa 减少了小鼠肝损伤标志物并改善了代谢功能障碍,通过调节脂质代谢和抑制炎症。

How strong is the evidence for Hairy agrimony?

The strongest finding for Hairy agrimony carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Hairy agrimony safe? What are the side effects?

No major safety issues are recorded for Hairy agrimony in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Hairy agrimony interact with medications?

No drug interactions are recorded for Hairy agrimony in our sources. This does not rule them out — check with a pharmacist.

Is Hairy agrimony a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Preliminary Data on the Senolytic Effects of Agrimonia pilosa Ledeb. Extract Containing Agrimols for Immunosenescence in Middle-Aged Humans: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Study. literature abstract metadata
  2. T2 Multi-target protective effects of Agrimonia pilosa Ledeb. against metabolic dysfunction-associated steatohepatitis in mice. literature abstract metadata
  3. T2 Variations of terpenes profiling and functional characterization of terpene synthases in Agrimonia pilosa. literature abstract metadata
  4. T2 Protective Effects of Agrimonia pilosa Ledeb. In Myocardial Fibrosis: Inhibition of Mitophagy Mediated by the FOXO Signaling Pathway. literature abstract metadata