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Acokanthera oblongifolia

Acokanthera oblongifolia

Acokanthera oblongifolia is a plant traditionally used in African medicine for treating snakebites, itching, and internal worms. It has been utilized in various indigenous practices across different regions of Africa. Scientific studies have shown that the plant contains several bioactive compounds, with Acovenoside A demonstrating potent antiviral activity against Newcastle disease virus and H5N1 influenza virus. Additionally, both Acovenoside A and acobioside A exhibited strong anti-proliferative and anti-angiogenic activities in certain cancer cell lines. However, the cardenolides identified from its leaves showed high cytotoxicity not only to cancer cells but also to normal cells, indicating potential toxicity concerns. The plant's stomatal rings influence guard cell mechanics by affecting stomatal pore depth during opening, though this finding is more related to plant physiology than medicinal use. No major safety issues or recorded drug interactions have been noted for Acokanthera oblongifolia thus far.

Auf einen Blick
Traditionell für
snakebites · jucken
Traditionen
westliche Phytotherapie
Beste Evidenz
D
Warnhinweise
—

Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.

Traditionelle Anwendung

  • snakebites westliche Phytotherapie T3 WIKIPEDIA
  • jucken westliche Phytotherapie T3 WIKIPEDIA
  • innere Würmer westliche Phytotherapie T3 WIKIPEDIA

Was die Wissenschaft sagt

  • Beides Acovenoside A und Acobioside A zeigten starke antiproliferative und anti-angiogene Aktivitäten gegenüber bestimmten Krebszellenlinien. D PMID
  • Die Studie identifizierte mehrere Cardenolide in den Blättern von Acokanthera oblongifolia, wobei eines eine hohe Zytotoxizität gegenüber Krebszellenlinien zeigte, aber auch bei normalen Zellen giftig war. D PMID
  • Die Studie zeigte an, dass Stomatalringe, sei es am Rand oder auf Vorsprüngen, die Mechanik der Wachtelzellen durch das Beeinflussen der Stomatalen-Poren-Tiefen während des Öffnungsprozesses beeinflussen. D EPMC
  • Vier Komponenten zeigten Antiviralmittelwirkung gegenüber dem Newcastle-Virus und dem Influenzavirus H5N1, wobei Acovenosid A die stärkste Wirkung hatte. D PMID

Frequently asked questions

What is Acokanthera oblongifolia?

Acokanthera oblongifolia (Acokanthera oblongifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Acokanthera oblongifolia traditionally used for?

Traditional sources record Acokanthera oblongifolia for: snakebites, jucken, innere Würmer. This reflects traditional use, not a proven medical treatment.

Which traditions use Acokanthera oblongifolia?

Acokanthera oblongifolia appears in these traditions in our sources: Western phytotherapy.

What does the scientific evidence say about Acokanthera oblongifolia?

4 sourced findings are recorded for Acokanthera oblongifolia; the strongest carries evidence grade D. For example: Beides Acovenoside A und Acobioside A zeigten starke antiproliferative und anti-angiogene Aktivitäten gegenüber bestimmten Krebszellenlinien.

How strong is the evidence for Acokanthera oblongifolia?

The strongest finding for Acokanthera oblongifolia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Acokanthera oblongifolia safe? What are the side effects?

No major safety issues are recorded for Acokanthera oblongifolia in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Acokanthera oblongifolia interact with medications?

No drug interactions are recorded for Acokanthera oblongifolia in our sources. This does not rule them out — check with a pharmacist.

Is Acokanthera oblongifolia a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Quellen

  1. T2 Influence of stomatal rings on movements of guard cells literature abstract metadata
  2. T2 Cytotoxic Cardenolides from the Leaves of Acokanthera oblongifolia. literature abstract metadata
  3. T2 In vitro chemotherapeutic and antiangiogenic properties of cardenolides from Acokanthera oblongifolia (Hochst.) Codd. literature abstract metadata
  4. T2 Cardenolides and pentacyclic triterpenes isolated from Acokanthera oblongifolia leaves: their biological activities with molecular docking study. literature abstract metadata
  5. T3 Acokanthera oblongifolia CC BY-SA 4.0