Acokanthera oblongifolia
Acokanthera oblongifolia
Acokanthera oblongifolia is a plant traditionally used in African medicine for treating snakebites, itching, and internal worms. It has been utilized in various indigenous practices across different regions of Africa. Scientific studies have shown that the plant contains several bioactive compounds, with Acovenoside A demonstrating potent antiviral activity against Newcastle disease virus and H5N1 influenza virus. Additionally, both Acovenoside A and acobioside A exhibited strong anti-proliferative and anti-angiogenic activities in certain cancer cell lines. However, the cardenolides identified from its leaves showed high cytotoxicity not only to cancer cells but also to normal cells, indicating potential toxicity concerns. The plant's stomatal rings influence guard cell mechanics by affecting stomatal pore depth during opening, though this finding is more related to plant physiology than medicinal use. No major safety issues or recorded drug interactions have been noted for Acokanthera oblongifolia thus far.
- Uso tradicional
- snakebites · picar
- Tradiciones
- fitoterapia occidental
- Mejor evidencia
- D
- Precauciones
- —
Solo información. El uso tradicional no significa eficacia probada. La evidencia y la seguridad varían — consulte las fuentes citadas.
Uso tradicional
- snakebites
- picar
- parásitos intestinales
Lo que dice la ciencia
- Ambos acovenoside A y acobioside A mostraron una actividad antiproliferativa y antiangiogénica fuerte contra ciertas líneas celulares de cáncer.
- El estudio identificó varios cardenolidos en las hojas de Acokanthera oblongifolia, con uno mostrando alta citotoxicidad contra líneas celulares cancerosas pero también toxicidad para células normales.
- El estudio encontró que los anillos estomáticos, ya sean marginales o en salientes, influyen en la mecánica de las células guardiana al afectar la profundidad del poro estomátkico durante el abertura.
- Cuatro compuestos mostraron actividad antiviral contra el virus de Newcastle y el influenza H5N1, siendo acovenoside A el más potente.
Frequently asked questions
What is Acokanthera oblongifolia?
Acokanthera oblongifolia (Acokanthera oblongifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Acokanthera oblongifolia traditionally used for?
Traditional sources record Acokanthera oblongifolia for: snakebites, picar, parásitos intestinales. This reflects traditional use, not a proven medical treatment.
Which traditions use Acokanthera oblongifolia?
Acokanthera oblongifolia appears in these traditions in our sources: Western phytotherapy.
What does the scientific evidence say about Acokanthera oblongifolia?
4 sourced findings are recorded for Acokanthera oblongifolia; the strongest carries evidence grade D. For example: Ambos acovenoside A y acobioside A mostraron una actividad antiproliferativa y antiangiogénica fuerte contra ciertas líneas celulares de cáncer.
How strong is the evidence for Acokanthera oblongifolia?
The strongest finding for Acokanthera oblongifolia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Acokanthera oblongifolia safe? What are the side effects?
No major safety issues are recorded for Acokanthera oblongifolia in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Acokanthera oblongifolia interact with medications?
No drug interactions are recorded for Acokanthera oblongifolia in our sources. This does not rule them out — check with a pharmacist.
Is Acokanthera oblongifolia a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Fuentes
- T2 Influence of stomatal rings on movements of guard cells literature abstract metadata
- T2 Cytotoxic Cardenolides from the Leaves of Acokanthera oblongifolia. literature abstract metadata
- T2 In vitro chemotherapeutic and antiangiogenic properties of cardenolides from Acokanthera oblongifolia (Hochst.) Codd. literature abstract metadata
- T2 Cardenolides and pentacyclic triterpenes isolated from Acokanthera oblongifolia leaves: their biological activities with molecular docking study. literature abstract metadata
- T3 Acokanthera oblongifolia CC BY-SA 4.0