FolkKB

Acokanthera oblongifolia

Acokanthera oblongifolia

Acokanthera oblongifolia is a plant traditionally used in African medicine for treating snakebites, itching, and internal worms. It has been utilized in various indigenous practices across different regions of Africa. Scientific studies have shown that the plant contains several bioactive compounds, with Acovenoside A demonstrating potent antiviral activity against Newcastle disease virus and H5N1 influenza virus. Additionally, both Acovenoside A and acobioside A exhibited strong anti-proliferative and anti-angiogenic activities in certain cancer cell lines. However, the cardenolides identified from its leaves showed high cytotoxicity not only to cancer cells but also to normal cells, indicating potential toxicity concerns. The plant's stomatal rings influence guard cell mechanics by affecting stomatal pore depth during opening, though this finding is more related to plant physiology than medicinal use. No major safety issues or recorded drug interactions have been noted for Acokanthera oblongifolia thus far.

速览
传统用于
snakebites · 痒
传统体系
西方植物疗法
最佳证据
D
注意事项
—

仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。

传统用途

科学怎么说

  • 两种化合物 acovenoside A 和 acobioside A 在某些癌细胞系中均表现出强烈的抗增殖和抗血管生成活性。 D PMID
  • 研究在Acokanthera oblongifolia的叶片中鉴定出了几种卡定诺利德，其中一种对癌细胞系显示出高细胞毒性，但同时也对正常细胞有毒性。 D PMID
  • 研究发现，无论是边缘还是在突出部位的气孔环，都会通过影响开闭过程中气孔深度来影响保卫细胞的机械特性。 D EPMC
  • 四种化合物显示出对抗新castle病病毒和H5N1流感病毒的抗病毒活性，其中Acovenoside A最为有效。 D PMID

Frequently asked questions

What is Acokanthera oblongifolia?

Acokanthera oblongifolia (Acokanthera oblongifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Acokanthera oblongifolia traditionally used for?

Traditional sources record Acokanthera oblongifolia for: snakebites, 痒, 肠道寄生虫. This reflects traditional use, not a proven medical treatment.

Which traditions use Acokanthera oblongifolia?

Acokanthera oblongifolia appears in these traditions in our sources: Western phytotherapy.

What does the scientific evidence say about Acokanthera oblongifolia?

4 sourced findings are recorded for Acokanthera oblongifolia; the strongest carries evidence grade D. For example: 两种化合物 acovenoside A 和 acobioside A 在某些癌细胞系中均表现出强烈的抗增殖和抗血管生成活性。

How strong is the evidence for Acokanthera oblongifolia?

The strongest finding for Acokanthera oblongifolia carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Acokanthera oblongifolia safe? What are the side effects?

No major safety issues are recorded for Acokanthera oblongifolia in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Acokanthera oblongifolia interact with medications?

No drug interactions are recorded for Acokanthera oblongifolia in our sources. This does not rule them out — check with a pharmacist.

Is Acokanthera oblongifolia a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

来源

  1. T2 Influence of stomatal rings on movements of guard cells literature abstract metadata
  2. T2 Cytotoxic Cardenolides from the Leaves of Acokanthera oblongifolia. literature abstract metadata
  3. T2 In vitro chemotherapeutic and antiangiogenic properties of cardenolides from Acokanthera oblongifolia (Hochst.) Codd. literature abstract metadata
  4. T2 Cardenolides and pentacyclic triterpenes isolated from Acokanthera oblongifolia leaves: their biological activities with molecular docking study. literature abstract metadata
  5. T3 Acokanthera oblongifolia CC BY-SA 4.0