FolkKB

Custard Apple

Annonaceae

Xylopia aethiopica is part of the Annonaceae family, traditionally with no recorded uses. Scientific evidence suggests that it may induce slight decreases in bilirubin levels and platelet counts at higher doses, potentially leading to thrombocytopenia and anemia. The methanolic extract and ethyl acetate fraction of Desmos chinensis leaves have shown significant analgesic, anti-pyretic, anti-inflammatory, and anti-arthritic activities. Regarding the Annonaceae family, a study noted that Caribbean Parkinson's disease patients, more exposed to Annonaceae fruits, exhibited slightly more severe motor and cognitive symptoms compared to mainland France patients, though this finding is not widely supported by other studies. Safety for Xylopia aethiopica has shown no major issues recorded. There are currently no reported drug interactions associated with the use of Desmos chinensis leaves or any members of the Annonaceae family.

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Beste Evidenz
B
Warnhinweise
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Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.

Was die Wissenschaft sagt

  • Xylopia aethiopica führte zu geringfügigen Abnahmen der Bilirubingehalte und Blutplättchenzahlen bei höheren Dosen, was eine mögliche Thrombozytopenie und Anämie suggerieren könnte. D PMID
  • Die Studie zeigte, dass der Methanolaussatz und die Ethyl-Acetat-Fraktion von Desmos chinensis Blättern eine signifikante Analgetische, Antiphlogistische, Antiinflamatorische und Antiarthritische Wirkung aufweisen. D PMID
  • Die Studie zeigte, dass bioaktive Stoffe aus Pflanzen, einschließlich denen der Familie Annonaceae, eine Antiprotozoiden-Aktivität gegen vernachlässigte tropische Krankheiten wie HAT, Chagadisease und Leishmanien zeigen. D PMID
  • Patienterkrankungen PD aus dem Karibischen Raum, die sich mehr auf Annonaceae-Früchte konzentrierten, zeigten leichte stärkere motorische und kognitive Symptome als Patienten in französischen Gebieten. B PMID

Frequently asked questions

What is Custard Apple?

Custard Apple (Annonaceae) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Custard Apple?

4 sourced findings are recorded for Custard Apple; the strongest carries evidence grade B. For example: Xylopia aethiopica führte zu geringfügigen Abnahmen der Bilirubingehalte und Blutplättchenzahlen bei höheren Dosen, was eine mögliche Thrombozytopenie und Anämie suggerieren könnte.

How strong is the evidence for Custard Apple?

The strongest finding for Custard Apple carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Custard Apple safe? What are the side effects?

No major safety issues are recorded for Custard Apple in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Custard Apple interact with medications?

No drug interactions are recorded for Custard Apple in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Custard Apple?

Custard Apple is also known as: Анноновые, Annonacées.

Is Custard Apple a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Quellen

  1. T2 Exploring the Anti-Nociceptive, Anti-Inflammatory, Anti-Pyretic, and Anti-Arthritic Activity of Methanolic Extract of Desmos chinensis and Its Different Solvent Fractions: In Vivo, In Vitro, and In Silico Intervention. literature abstract metadata
  2. T2 Molecular Mechanisms of Natural Antiprotozoal Compounds: Emerging Strategies for Neglected Tropical Diseases. literature abstract metadata
  3. T2 Acute (14-Day) and Subchronic (90-Day) Toxicity Evaluation of the Dried Fruit Spice Xylopia aethiopica (Dunal) A. Rich. (Annonaceae) in Male and Female Wistar Rats. literature abstract metadata
  4. T2 The Clinical Effect of Annonaceae Fruit Consumption on Caribbean Parkinson's Disease Severity. literature abstract metadata