Plectranthus hadiensis
Plectranthus hadiensis
Plectranthus hadiensis, also known as Royalty or Kafir Royal, is a plant native to Madagascar. While traditional uses for this plant are not well-documented, studies have shown promising results in its biological activity. A study identified 26 terpene synthase genes in Plectranthus hadiensis and confirmed the functional expression of one gene (PhTPS1) involved in limonene synthesis. Additionally, research has found that a compound from this plant, Roy, demonstrated significant antitumor activity against glioblastoma cell lines through mechanisms such as G2/M arrest and apoptosis induction. However, scientific evidence for its traditional medicinal uses is currently limited. Safety profiles indicate no major issues have been recorded, and there are no known drug interactions reported at present.
- Beste Evidenz
- D
- Warnhinweise
- —
Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.
Was die Wissenschaft sagt
- Die Studie erkannte 26 Terpen-Synthasen-Gen in Plectranthus hadiensis und bestätigte die funktionalen Ausdrucksformen eines Genes (PhTPS1), das an der Limonen-Synthese beteiligt ist.
- Die Studie bot die erste vollständige Chloroplasten genomsequenz von Plectranthus hadiensis und fand seine engste phylogenetische Verwandtschaft mit Isodon.
- Roy aus Plectranthus hadiensis zeigte eine signifikante Antitumoralität gegenüber Glioblastomzelllinien durch die Verhinderung der G2/M-Phase und die Induktion von Apoptose.
- Roy reduzierte die Größe der Glioblastom-Spheroiden und die metabolische Aktivität, während er die mRNA-Expression von IL-6/STAT3/JAK2 modulierte.
Frequently asked questions
What is Plectranthus hadiensis?
Plectranthus hadiensis (Plectranthus hadiensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Plectranthus hadiensis?
4 sourced findings are recorded for Plectranthus hadiensis; the strongest carries evidence grade D. For example: Die Studie erkannte 26 Terpen-Synthasen-Gen in Plectranthus hadiensis und bestätigte die funktionalen Ausdrucksformen eines Genes (PhTPS1), das an der Limonen-Synthese beteiligt ist.
How strong is the evidence for Plectranthus hadiensis?
The strongest finding for Plectranthus hadiensis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Plectranthus hadiensis safe? What are the side effects?
No major safety issues are recorded for Plectranthus hadiensis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Plectranthus hadiensis interact with medications?
No drug interactions are recorded for Plectranthus hadiensis in our sources. This does not rule them out — check with a pharmacist.
Is Plectranthus hadiensis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Quellen
- T2 The complete chloroplast genome sequence of Plectranthus hadiensis (Lamiaceae) and phylogenetic analysis. literature abstract metadata
- T2 Unveiling the antitumor mechanism of 7α-acetoxy-6β-hydroxyroyleanone from Plectranthus hadiensis in glioblastoma. literature abstract metadata
- T2 7α-acetoxy-6β-hydroxyroyleanone (Roy) modulates IL-6/STAT3/JAK2 mRNA expression and suppresses tumor growth in glioblastoma cell models. literature abstract metadata
- T2 Transcriptional and functional characterization of terpene synthase genes of the aromatic plant Plectranthus hadiensis. literature abstract metadata