Plectranthus hadiensis
Plectranthus hadiensis
Plectranthus hadiensis, also known as Roy, is a plant traditionally used in some African herbal practices. While its specific traditional uses are not well-documented, it has been studied for potential medicinal properties. Scientific research indicates that Plectranthus hadiensis contains terpene synthase genes, particularly PhTPS1 involved in limonene synthesis, and provides the first complete chloroplast genome sequence of this plant, linking it closely to Isodon species. Notably, extracts from Plectranthus hadiensis have shown significant antitumor activity against glioblastoma cell lines through mechanisms such as G2/M arrest and apoptosis induction, though more research is needed for broader applications. No major safety concerns or drug interactions have been recorded thus far, but further investigation is warranted to fully understand its potential benefits and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified 26 terpene synthase genes in Plectranthus hadiensis, confirming the functional expression of one gene (PhTPS1) involved in limonene synthesis.
- The study provided the first complete chloroplast genome sequence of Plectranthus hadiensis and found its closest phylogenetic relationship with Isodon.
- Roy from Plectranthus hadiensis showed significant antitumor activity against glioblastoma cell lines through G2/M arrest and apoptosis induction.
- Roy significantly reduced glioblastoma spheroid size and metabolic activity while modulating IL-6/STAT3/JAK2 mRNA expression.
Frequently asked questions
What is Plectranthus hadiensis?
Plectranthus hadiensis (Plectranthus hadiensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Plectranthus hadiensis?
4 sourced findings are recorded for Plectranthus hadiensis; the strongest carries evidence grade D. For example: The study identified 26 terpene synthase genes in Plectranthus hadiensis, confirming the functional expression of one gene (PhTPS1) involved in limonene synthesis.
How strong is the evidence for Plectranthus hadiensis?
The strongest finding for Plectranthus hadiensis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Plectranthus hadiensis safe? What are the side effects?
No major safety issues are recorded for Plectranthus hadiensis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Plectranthus hadiensis interact with medications?
No drug interactions are recorded for Plectranthus hadiensis in our sources. This does not rule them out — check with a pharmacist.
Is Plectranthus hadiensis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 The complete chloroplast genome sequence of Plectranthus hadiensis (Lamiaceae) and phylogenetic analysis. literature abstract metadata
- T2 Unveiling the antitumor mechanism of 7α-acetoxy-6β-hydroxyroyleanone from Plectranthus hadiensis in glioblastoma. literature abstract metadata
- T2 7α-acetoxy-6β-hydroxyroyleanone (Roy) modulates IL-6/STAT3/JAK2 mRNA expression and suppresses tumor growth in glioblastoma cell models. literature abstract metadata
- T2 Transcriptional and functional characterization of terpene synthase genes of the aromatic plant Plectranthus hadiensis. literature abstract metadata