Plectranthus hadiensis
Plectranthus hadiensis
Plectranthus hadiensis, also known as Royalty or Kafir Royal, is a plant native to Madagascar. While traditional uses for this plant are not well-documented, studies have shown promising results in its biological activity. A study identified 26 terpene synthase genes in Plectranthus hadiensis and confirmed the functional expression of one gene (PhTPS1) involved in limonene synthesis. Additionally, research has found that a compound from this plant, Roy, demonstrated significant antitumor activity against glioblastoma cell lines through mechanisms such as G2/M arrest and apoptosis induction. However, scientific evidence for its traditional medicinal uses is currently limited. Safety profiles indicate no major issues have been recorded, and there are no known drug interactions reported at present.
- 最佳证据
- D
- 注意事项
- —
仅供参考。传统用法并不代表已被证实有效。证据与安全性各不相同，请查阅所引来源。
科学怎么说
- 研究在Plectranthus hadiensis中鉴定了26个萜类合酶基因，证实了一个参与柠檬烯合成的基因（PhTPS1）的功能表达。
- 该研究提供了第一个完整的Plectranthus hadiensis叶绿体基因组序列，并发现其与Isodon的最近亲缘关系。
- 来自Plectranthus hadiensis的Roy在G2/M期阻滞和诱导凋亡方面对胶质母细胞瘤细胞系显示出显著的抗肿瘤活性。
- 罗伊显著减少了胶质母细胞瘤球体的大小和代谢活性，同时调节IL-6/STAT3/JAK2 mRNA表达。
Frequently asked questions
What is Plectranthus hadiensis?
Plectranthus hadiensis (Plectranthus hadiensis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Plectranthus hadiensis?
4 sourced findings are recorded for Plectranthus hadiensis; the strongest carries evidence grade D. For example: 研究在Plectranthus hadiensis中鉴定了26个萜类合酶基因，证实了一个参与柠檬烯合成的基因（PhTPS1）的功能表达。
How strong is the evidence for Plectranthus hadiensis?
The strongest finding for Plectranthus hadiensis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Plectranthus hadiensis safe? What are the side effects?
No major safety issues are recorded for Plectranthus hadiensis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Plectranthus hadiensis interact with medications?
No drug interactions are recorded for Plectranthus hadiensis in our sources. This does not rule them out — check with a pharmacist.
Is Plectranthus hadiensis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
来源
- T2 The complete chloroplast genome sequence of Plectranthus hadiensis (Lamiaceae) and phylogenetic analysis. literature abstract metadata
- T2 Unveiling the antitumor mechanism of 7α-acetoxy-6β-hydroxyroyleanone from Plectranthus hadiensis in glioblastoma. literature abstract metadata
- T2 7α-acetoxy-6β-hydroxyroyleanone (Roy) modulates IL-6/STAT3/JAK2 mRNA expression and suppresses tumor growth in glioblastoma cell models. literature abstract metadata
- T2 Transcriptional and functional characterization of terpene synthase genes of the aromatic plant Plectranthus hadiensis. literature abstract metadata