Beach vitex

Vitex rotundifolia

Vitex rotundifolia is a plant native to regions of Africa and Asia. While its traditional medicinal uses are not well-documented, preliminary scientific research has shown promise in various areas. The essential oil from its cone inhibited melanin synthesis and transport-related responses in B16BL6 melanoma cells without affecting cell viability, indicating potential skin health applications. Additionally, the processed fruit of Vitex rotundifolia demonstrated comparable antioxidant activity to raw fruit extracts and contained similar metabolites, suggesting it may have antioxidant properties. Advanced analytical techniques identified 29 differential compounds between raw and processed fruits, highlighting its chemical diversity. Casticin from this plant was found to reduce glutamate release in rat hippocampal synaptosomes by decreasing synaptic vesicle exocytosis, which could potentially impact neurochemical processes. No major safety issues or drug interactions have been recorded for Vitex rotundifolia thus far.

Auf einen Blick
Beste Evidenz
D
Warnhinweise

Nur zur Information. Traditionelle Anwendung bedeutet keine nachgewiesene Wirksamkeit. Evidenz und Sicherheit variieren — siehe die angegebenen Quellen.

Was die Wissenschaft sagt

  • Casticin aus Vitex rotundifolia reduziert die Glutamatfreisetzung in den Synaptosomen des Rattenehippokampus durch Inhibition der N-Typ-Kaliumkanäle und eine Verringerung der Synapsenvesikel-Exkytose. D PMID
  • Das Konen-Öl von Vitex rotundifolia hat die Melaninfektion und Transportreaktionen in B16BL6-Melanomzellen gehemmt, ohne die Zellviabilität zu beeinflussen. D PMID
  • Die PDR von Vitex rotundifolia zeigte vergleichbare Antioxidationsaktivität wie frische Fruchtextrakte und enthielt ähnliche Metaboliten. D PMID
  • Twenty-nine differential compounds were identified between raw and processed Vitex rotundifolia fruits using advanced analytical techniques. D PMID

Frequently asked questions

What is Beach vitex?

Beach vitex (Vitex rotundifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Beach vitex?

4 sourced findings are recorded for Beach vitex; the strongest carries evidence grade D. For example: Casticin aus Vitex rotundifolia reduziert die Glutamatfreisetzung in den Synaptosomen des Rattenehippokampus durch Inhibition der N-Typ-Kaliumkanäle und eine Verringerung der Synapsenvesikel-Exkytose.

How strong is the evidence for Beach vitex?

The strongest finding for Beach vitex carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Beach vitex safe? What are the side effects?

No major safety issues are recorded for Beach vitex in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Beach vitex interact with medications?

No drug interactions are recorded for Beach vitex in our sources. This does not rule them out — check with a pharmacist.

Is Beach vitex a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Quellen

  1. T2 Casticin inhibits the release of synaptic vesicular glutamate from rat hippocampal nerve terminals. literature abstract metadata
  2. T2 Multichemical Analytical Strategy for Screening Key Differential Compound between Raw and Processed Viticis fructus. literature abstract metadata
  3. T2 Chemical profiling and sustainable valorization of post-distillation residues of Vitex rotundifolia. literature abstract metadata
  4. T2 Depigmenting Effects of Vitex rotundifolia Cone Essential Oil in Melanocytes and Its Chemical Composition. literature abstract metadata