FolkKB

Beach vitex

Vitex rotundifolia

Vitex rotundifolia is a plant species with roots in traditional medicine. It is traditionally utilized for the management of fever. Scientific evidence regarding its therapeutic efficacy is limited, though certain studies suggest that the compound casticin may reduce glutamate release in rat hippocampal synaptosomes by inhibiting N-type Ca2+ channels. Additionally, research indicates that its cone essential oil may inhibit melanin synthesis in melanoma cells, and its processed fruits maintain antioxidant activity comparable to raw extracts. No major safety issues or notable drug interactions have been recorded in the available data.

At a glance
Traditionally for
fever
Traditions
traditional
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

Traditional use

What the science says

  • Casticin, from Vitex rotundifolia, reduces glutamate release in rat hippocampal synaptosomes by inhibiting N-type Ca2+ channels and decreasing synaptic vesicle exocytosis. D PMID
  • Vitex rotundifolia cone essential oil inhibited melanin synthesis and transport-related responses in B16BL6 melanoma cells without affecting cell viability. D PMID
  • PDR from Vitex rotundifolia showed comparable antioxidant activity to raw fruit extracts and contained similar metabolites. D PMID
  • Twenty-nine differential compounds were identified between raw and processed Vitex rotundifolia fruits using advanced analytical techniques. D PMID

Frequently asked questions

What is Beach vitex?

Beach vitex (Vitex rotundifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Beach vitex traditionally used for?

Traditional sources record Beach vitex for: fever. This reflects traditional use, not a proven medical treatment.

Which traditions use Beach vitex?

Beach vitex appears in these traditions in our sources: traditional.

What does the scientific evidence say about Beach vitex?

4 sourced findings are recorded for Beach vitex; the strongest carries evidence grade D. For example: Casticin, from Vitex rotundifolia, reduces glutamate release in rat hippocampal synaptosomes by inhibiting N-type Ca2+ channels and decreasing synaptic vesicle exocytosis.

How strong is the evidence for Beach vitex?

The strongest finding for Beach vitex carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Beach vitex safe? What are the side effects?

No major safety issues are recorded for Beach vitex in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Beach vitex interact with medications?

No drug interactions are recorded for Beach vitex in our sources. This does not rule them out — check with a pharmacist.

Is Beach vitex a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Casticin inhibits the release of synaptic vesicular glutamate from rat hippocampal nerve terminals. literature abstract metadata
  3. T2 Multichemical Analytical Strategy for Screening Key Differential Compound between Raw and Processed Viticis fructus. literature abstract metadata
  4. T2 Chemical profiling and sustainable valorization of post-distillation residues of Vitex rotundifolia. literature abstract metadata
  5. T2 Depigmenting Effects of Vitex rotundifolia Cone Essential Oil in Melanocytes and Its Chemical Composition. literature abstract metadata

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