Holly-leaved acanthus, Sea holly, Holly mangrove

Acanthus ilicifolius

Acanthus ilicifolius is a plant traditionally used in various Asian and Mediterranean cultures for treating asthma and rheumatism. Scientific research has shown that acteoside, a bioactive compound from Acanthus ilicifolius, may inhibit glutamine synthetase to alleviate doxorubicin-induced cardiotoxicity by suppressing ferroptosis, indicating potential cardiovascular benefits. However, the broader evidence supporting its traditional uses for asthma and rheumatism is limited and requires further investigation. No significant safety concerns or drug interactions have been recorded, but given the lack of extensive clinical trials, caution should be exercised when using Acanthus ilicifolius in a therapeutic context.

At a glance
Traditionally for
asthma · rheumatism
Traditions
TCM
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

Traditional use

What the science says

  • Ilicifolius acid A significantly alleviates dextran sulfate sodium-induced colitis symptoms and promotes intestinal barrier repair in mice. D PMID
  • Acteoside, a bioactive compound from Acanthus ilicifolius, was found to alleviate doxorubicin-induced cardiotoxicity by inhibiting glutamine synthetase and suppressing ferroptosis. D PMID
  • The introduction of Sonneratia caseolaris increased sediment organic carbon content and altered carbon-fixing bacterial community composition in mangrove ecosystems. D PMID
  • The study generated genome assemblies for three Acanthus species, revealing a whole-genome duplication event and expansions in genes related to root adaptation. D PMID
  • The study found that Acanthus ilicifolius intercepted about 40% of floating microplastics during normal conditions but resuspended them during typhoons. D PMID

Frequently asked questions

What is Holly-leaved acanthus, Sea holly, Holly mangrove?

Holly-leaved acanthus, Sea holly, Holly mangrove (Acanthus ilicifolius) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Holly-leaved acanthus, Sea holly, Holly mangrove traditionally used for?

Traditional sources record Holly-leaved acanthus, Sea holly, Holly mangrove for: asthma, rheumatism. This reflects traditional use, not a proven medical treatment.

Which traditions use Holly-leaved acanthus, Sea holly, Holly mangrove?

Holly-leaved acanthus, Sea holly, Holly mangrove appears in these traditions in our sources: TCM.

What does the scientific evidence say about Holly-leaved acanthus, Sea holly, Holly mangrove?

5 sourced findings are recorded for Holly-leaved acanthus, Sea holly, Holly mangrove; the strongest carries evidence grade D. For example: Ilicifolius acid A significantly alleviates dextran sulfate sodium-induced colitis symptoms and promotes intestinal barrier repair in mice.

How strong is the evidence for Holly-leaved acanthus, Sea holly, Holly mangrove?

The strongest finding for Holly-leaved acanthus, Sea holly, Holly mangrove carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Holly-leaved acanthus, Sea holly, Holly mangrove safe? What are the side effects?

No major safety issues are recorded for Holly-leaved acanthus, Sea holly, Holly mangrove in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Holly-leaved acanthus, Sea holly, Holly mangrove interact with medications?

No drug interactions are recorded for Holly-leaved acanthus, Sea holly, Holly mangrove in our sources. This does not rule them out — check with a pharmacist.

Is Holly-leaved acanthus, Sea holly, Holly mangrove a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Therapeutic effects of Ilicifolius acid a in murine ulcerative colitis. literature abstract metadata
  2. T2 New insights into sink-source dynamics of mangrove for microplastics: Quantitative evidences from field observation and resuspension simulation. literature abstract metadata
  3. T2 Genome Assembly of Three Shrub Mangroves in the Genus Acanthus Reveals Two Polyploidy Events and Expansion of Genes Linked to Root Adaptation in Coastal Habitats. literature abstract metadata
  4. T2 Acteoside targeting glutamine synthetase ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis. literature abstract metadata
  5. T2 Carbon-fixing bacteria and sediment organic carbon response to the introduction of mangrove plant Sonneratia caseolaris. literature abstract metadata
  6. T3 Acanthus ilicifolius CC BY-SA 4.0