Indian Aspen
Acronychia pedunculata
Acronychia pedunculata is a plant native to Southeast Asia and Australia. While traditional use of this plant for medicinal purposes has not been extensively documented, studies have shown promising results in various areas. Scientific evidence indicates that Acronychia pedunculata exhibits potential anti-cancer properties, as it significantly improved cell viability and modulated apoptosis-related proteins in glutamate-induced neuroblastoma SH-SY5Y cells. Additionally, compounds from the flowers of this plant demonstrated activity against certain bacterial strains, suggesting possible antimicrobial applications. Leaf essential oils were found to have both anti-cancer and anti-inflammatory effects, further highlighting its potential medicinal uses. Notably, four new Microdochium species (M. acronychicola, M. brevisporum, M. chinense, and M. wuzhishanense) have been identified from Acronychia pedunculata in Hainan, China. Safety concerns do not appear to be significant based on current data, and there are no recorded drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- AVT from Acronychia pedunculata significantly improved cell viability and modulated apoptosis-related proteins in glutamate-induced neuroblastoma SH-SY5Y cells.
- The study identified chemical compositions and assessed anti-cancer and anti-inflammatory effects of leaf essential oils from Acronychia pedunculata and other Rutaceae species, suggesting potential medicinal uses.
- Four new Microdochium species (M. acronychicola, M. brevisporum, M. chinense, M. wuzhishanense) were identified from Acronychia pedunculata in Hainan, China.
- Seven novel compounds were isolated from Acronychia pedunculata and showed inhibitory activities against angiogenesis.
- Acronyculatin S (1) and demethylacrovestone (2) showed significant antibacterial activity against methicillin-resistant Staphylococcus aureus and Bacillus subtilis.
Frequently asked questions
What is Indian Aspen?
Indian Aspen (Acronychia pedunculata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Indian Aspen?
5 sourced findings are recorded for Indian Aspen; the strongest carries evidence grade D. For example: AVT from Acronychia pedunculata significantly improved cell viability and modulated apoptosis-related proteins in glutamate-induced neuroblastoma SH-SY5Y cells.
How strong is the evidence for Indian Aspen?
The strongest finding for Indian Aspen carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Indian Aspen safe? What are the side effects?
No major safety issues are recorded for Indian Aspen in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Indian Aspen interact with medications?
No drug interactions are recorded for Indian Aspen in our sources. This does not rule them out — check with a pharmacist.
Is Indian Aspen a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Chemical Compositions, Molecular Docking, Anti-Inflammatory, and Anti-Cancer Effects of the Leaf Essential Oils Isolated from Three Species of the Rutaceae Family in Vietnam. literature abstract metadata
- T2 Acronyculatin S, a polyphenolic isoprenylated acetophenone benzofuran with antibacterial properties from the flowers of Acronychia pedunculata. literature abstract metadata
- T2 Acronynoids A-G, novel prenylated acetophenone-based meroterpenoids with angiogenesis inhibitory activities from Acronychia pedunculata. literature abstract metadata
- T2 Neuroprotective effects of acetophenone dimers from Acronychia pedunculata on human neuroblastoma SH-SY5Y cells in glutamate-induced apoptosis. literature abstract metadata
- T2 Four new species of Microdochium (Microdochiaceae, Xylariales) based on morphology and multilocus phylogeny from Hainan, China. literature abstract metadata