Allamanda cathartica
Allamanda cathartica
Allamanda cathartica is a plant traditionally found in tropical regions of Central and South America. While its use in traditional medicine has not been extensively documented, studies have identified several bioactive compounds with potential health benefits. Research indicates that Allamanda cathartica leaf extracts may inhibit α-amylase and α-glucosidase enzymes, which could be beneficial for managing blood sugar levels. Additionally, the plant's leaf extract showed a significant reduction in serum testosterone levels and impaired germ cell proliferation due to downregulated steroidogenic protein expressions, suggesting potential effects on hormonal balance. In diabetic mice, Allamanda cathartica reduced blood glucose levels by 70.19% at 400 mg/kg, comparable to the effect of metformin (85.84%). The study also detailed the ontogenesis and chemical composition of laticifers in the plant, noting their distribution and latex content. Safety concerns for Allamanda cathartica are currently unreported, with no major issues recorded. There is also no evidence of significant drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study describes the ontogenesis of laticifers and the chemical composition of stem latex in Allamanda cathartica.
- The study identified five bioactive compounds from Allamanda cathartica leaves, showing notable inhibitory activity against α-amylase and α-glucosidase enzymes.
- MLEAC treatment resulted in reduced serum testosterone levels and impaired germ cell proliferation due to downregulated steroidogenic protein expressions.
- Allamanda cathartica leaf extracts reduced blood glucose levels in diabetic mice by 70.19% at 400 mg/kg, comparable to metformin's 85.84%.
Frequently asked questions
What is Allamanda cathartica?
Allamanda cathartica (Allamanda cathartica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Allamanda cathartica?
4 sourced findings are recorded for Allamanda cathartica; the strongest carries evidence grade D. For example: The study describes the ontogenesis of laticifers and the chemical composition of stem latex in Allamanda cathartica.
How strong is the evidence for Allamanda cathartica?
The strongest finding for Allamanda cathartica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Allamanda cathartica safe? What are the side effects?
No major safety issues are recorded for Allamanda cathartica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Allamanda cathartica interact with medications?
No drug interactions are recorded for Allamanda cathartica in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Allamanda cathartica?
Allamanda cathartica is also known as: Алламанда слабительная.
Is Allamanda cathartica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Ontogenesis of the anastomosed laticifers of Allamanda cathartica (Apocynaceae) and the chemical nature of the stem latex. literature abstract metadata
- T2 Optimization of the extraction methods and evaluation of the hypoglycemic effect of Adhatoda Zeylanica extracts on artificially induced diabetic mice. literature abstract metadata
- T2 Anti-androgenic and anti-proliferative properties of methanolic leaf extract of Allamanda cathartica Linn. in adult mouse testis: Evidences from in vivo and in silico studies. literature abstract metadata
- T2 Structural Characterization, In Vitro Antidiabetic Activity, and Molecular Docking Studies of Isolated Compounds From Allamanda cathartica. literature abstract metadata