Deviltree
Alstonia macrophylla
Alstonia macrophylla is a plant traditionally used in various Southeast Asian and Pacific Island cultures, though its specific traditional medicinal uses are not well-documented. Scientific studies have identified eleven novel monoterpenoid bisindole alkaloids from the plant, which show potential for AChE inhibitory and cytotoxic activities. Additionally, distinct microbial community profiles were observed across different leaf types of Alstonia macrophylla, indicating its ecological significance. Notably, Ae. albopictus coexisted with 11 different species while avoiding larvae of Cx. fuscanus, Cx. uniformis, and Tripteroides affinis in tree holes of specific host plants, suggesting the plant may have repellent or larvicidal properties. While no major safety issues or drug interactions have been recorded, further research is needed to fully understand its potential applications and effects.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Ae. albopictus coexisted with 11 different species while avoiding larvae of Cx. fuscanus, Cx. uniformis, and Tripteroides affinis in tree holes of Alstonia macrophylla and other trees.
- Eleven monoterpenoid bisindole alkaloids were isolated from Alstonia macrophylla, with some showing potential AChE inhibitory and cytotoxic activity.
- Distinct microbial community profiles were observed across different leaf types, with Alstonia macrophylla showing high bacterial species richness.
- Three unusual ajmaline-macroline type bisindole alkaloids, alsmaphylines A-C, were isolated from Alstonia macrophylla.
Frequently asked questions
What is Deviltree?
Deviltree (Alstonia macrophylla) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Deviltree?
4 sourced findings are recorded for Deviltree; the strongest carries evidence grade D. For example: Ae. albopictus coexisted with 11 different species while avoiding larvae of Cx. fuscanus, Cx. uniformis, and Tripteroides affinis in tree holes of Alstonia macrophylla and other trees.
How strong is the evidence for Deviltree?
The strongest finding for Deviltree carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Deviltree safe? What are the side effects?
No major safety issues are recorded for Deviltree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Deviltree interact with medications?
No drug interactions are recorded for Deviltree in our sources. This does not rule them out — check with a pharmacist.
Is Deviltree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Breeding site selection and co-existing patterns of tropical mosquitoes. literature abstract metadata
- T2 Discovery of Unusual Ajmaline-Macroline Type Bisindole Alkaloids from Alstonia macrophylla by Building Blocks-Based Molecular Networking. literature abstract metadata
- T2 Alstomaphylines A-K, monoterpenoid bisindole alkaloids from Alstonia macrophylla with AChE inhibitory activity and cytotoxicity. literature abstract metadata
- T2 Diversity and functional potential of bacterial and fungal endophytes in traditional food wrapping leaves reveal implications for artisanal food safety and quality. literature abstract metadata