Anemarrhena asphodeloides
Anemarrhena asphodeloides
Anemarrhena asphodeloides, a traditional Chinese medicine plant commonly known as "Zhimu," is traditionally used for various conditions but specific uses are not well-documented in its tradition. Scientific evidence suggests potential benefits such as improving renal function and reducing histopathological injury by suppressing the NF-κB/NLRP3 inflammasome axis, inhibiting PEDV infection through ROS/caspase-3 dependent apoptosis, and potentially targeting the HSP90/PI3K/Akt/mTOR axis to exert anti-oral squamous cell carcinoma effects. However, these findings are preliminary and more research is needed for broader application. No major safety concerns or drug interactions have been recorded, but further investigation is warranted to fully understand its potential uses and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Sar dose-dependently improved renal function and reduced histopathological injury in rats with RIRI by suppressing the NF-κB/NLRP3 inflammasome axis.
- Anemarrhena asphodeloides polysaccharide can effectively inhibit PEDV infection in a dose-dependent manner by targeting ROS/caspase-3 dependent apoptosis.
- The study identified eight mitochondria-related differentially expressed genes associated with Zhimu-Huangbai treatment in type 2 diabetes.
- The study found that hippeastrine from Anemarrhena asphodeloides potentially targets the HSP90/PI3K/Akt/mTOR axis to exert anti-OSCC effects in vitro.
Frequently asked questions
What is Anemarrhena asphodeloides?
Anemarrhena asphodeloides (Anemarrhena asphodeloides) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Anemarrhena asphodeloides?
4 sourced findings are recorded for Anemarrhena asphodeloides; the strongest carries evidence grade D. For example: Sar dose-dependently improved renal function and reduced histopathological injury in rats with RIRI by suppressing the NF-κB/NLRP3 inflammasome axis.
How strong is the evidence for Anemarrhena asphodeloides?
The strongest finding for Anemarrhena asphodeloides carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Anemarrhena asphodeloides safe? What are the side effects?
No major safety issues are recorded for Anemarrhena asphodeloides in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Anemarrhena asphodeloides interact with medications?
No drug interactions are recorded for Anemarrhena asphodeloides in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Anemarrhena asphodeloides?
Anemarrhena asphodeloides is also known as: Анемаррена асфоделовидная.
Is Anemarrhena asphodeloides a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Identification of mitochondria-related key genes in type 2 diabetes mellitus and elucidation of the Zhimu-Huangbai herb Pair's mechanism: an integrated approach of bioinformatics, machine learning, and experimental validation. literature abstract metadata
- T2 Anemarrhena asphodeloides Polysaccharide Exerts Antiviral Activity Against Porcine Epidemic Diarrhea Virus Targeting ROS/Caspase-3 Dependent Apoptosis. literature abstract metadata
- T2 Sarsasapogenin attenuates renal ischemia-reperfusion injury by inhibiting the NF-κB pathway and NLRP3 inflammasome-mediated pyroptosis. literature abstract metadata
- T2 Integrative Database-Driven In Silico and In Vitro Study of Anemarrhena asphodeloides Bunge Highlighting Hippeastrine as a Regulator of the HSP90/PI3K/Akt/mTOR Axis in Oral Squamous Cell Carcinoma. literature abstract metadata