Cherimoya

Annona cherimola

Annona cherimola, commonly known as the cherimoya, is a tropical evergreen tree native to the Andes region of South America. While its traditional uses are not well-documented in specific medical traditions, studies have shown potential antihyperglycemic effects through various mechanisms. For instance, polyphenolic extracts (PEEAcL) from the fruit demonstrated significant antihyperglycemic activity in diabetic mice, possibly by inhibiting SGLT-1 and α-glucosidase. Additionally, aqueous leaf extracts showed similar beneficial effects on blood sugar levels, either alone or when combined with metformin. However, scientific evidence is limited, and more research is needed to confirm these findings. No major safety concerns have been reported for Annona cherimola, nor are there any recorded drug interactions.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • PEEAcL showed significant antihyperglycemic activity through potential SGLT-1 and α-glucosidase inhibition. D PMID
  • Key genes involved in female germline development show both conservation and divergence between Annona cherimola and Arabidopsis. D PMID
  • Aqueous extracts from Annona cherimola leaves showed significant antihyperglycemic activity alone or combined with metformin in mice. D PMID
  • This study found that red imported fire ant invasion did not significantly alter aerial arthropod diversity in cherimoya orchards. D PMID

Frequently asked questions

What is Cherimoya?

Cherimoya (Annona cherimola) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Cherimoya?

4 sourced findings are recorded for Cherimoya; the strongest carries evidence grade D. For example: PEEAcL showed significant antihyperglycemic activity through potential SGLT-1 and α-glucosidase inhibition.

How strong is the evidence for Cherimoya?

The strongest finding for Cherimoya carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Cherimoya safe? What are the side effects?

No major safety issues are recorded for Cherimoya in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Cherimoya interact with medications?

No drug interactions are recorded for Cherimoya in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Cherimoya?

Cherimoya is also known as: Черимойя, Anone chérimolier, Chérimole, Chérimolier, Chérimoyer.

Is Cherimoya a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Aqueous Extracts and Flavonoids Obtained from Annona cherimola Miller as Antidiabetic Treatments Alone and in Combination with Antidiabetic Drugs: In Vivo and In Silico Studies. literature abstract metadata
  2. T2 Comparative insights into molecular pathways influencing germline development in early-divergent angiosperms. literature abstract metadata
  3. T2 Biodiversity dynamics of aerially collected arthropods in Solenopsis invicta (Hymenoptera: Formicidae) invaded and excluded orchard agro-ecosystems. literature abstract metadata
  4. T2 Understanding the Antihyperglycemic Activity of Annona cherimola Leaves. An Edible and Medicinal Plant in Mexico: In Vivo and Ex-Vivo Studies. literature abstract metadata