yellow-fruit moonseed
Arcangelisia flava
Arcangelisia flava is a woody climber used in various traditional medicinal practices. It is traditionally applied to treat conditions such as dyspepsia, fever, jaundice, wounds, ulcers, and skin itches, as well as for its potential germicidal and vermifuge properties. Scientific evidence suggests some potential, as oxo berberine from the root extract has shown possible anti-cancer activity in certain pathways, and stem extracts have demonstrated some anti-inflammatory effects in animal models. Additionally, certain compounds show varying antifungal properties against Candida species, and some endophytic bacteria associated with the plant exhibit antimicrobial activity. No major safety issues or notable drug interactions have been recorded.
- Traditionally for
- dyspepsia · fever
- Traditions
- traditional
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- dyspepsia
- fever
- germicide
- itch
- jaundice
- rhinitis
- smallpox
- stomatitis
- ulcer
- vermifuge
- wounds
What the science says
- Oxo berberine from Arcangelisia flava root extract showed potential anti-cancer activity by interacting with multiple breast cancer-related genes and pathways.
- Compounds from Arcangelisia flava showed antifungal properties against Candida species with varying effectiveness.
- The study found that a 70% ethanol extract of Arcangelisia flava stems inhibited NO production in cells and reduced IL-1β levels, joint swelling, and latency time in rats.
- Four out of 29 isolated endophytic bacteria from Arcangelisia flava showed potential antimicrobial activity, with Bacillus cereus AKEBG23 being the most effective.
Frequently asked questions
What is yellow-fruit moonseed?
yellow-fruit moonseed (Arcangelisia flava) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is yellow-fruit moonseed traditionally used for?
Traditional sources record yellow-fruit moonseed for: dyspepsia, fever, germicide, itch, jaundice, rhinitis. This reflects traditional use, not a proven medical treatment.
Which traditions use yellow-fruit moonseed?
yellow-fruit moonseed appears in these traditions in our sources: traditional.
What does the scientific evidence say about yellow-fruit moonseed?
4 sourced findings are recorded for yellow-fruit moonseed; the strongest carries evidence grade D. For example: Oxo berberine from Arcangelisia flava root extract showed potential anti-cancer activity by interacting with multiple breast cancer-related genes and pathways.
How strong is the evidence for yellow-fruit moonseed?
The strongest finding for yellow-fruit moonseed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is yellow-fruit moonseed safe? What are the side effects?
No major safety issues are recorded for yellow-fruit moonseed in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does yellow-fruit moonseed interact with medications?
No drug interactions are recorded for yellow-fruit moonseed in our sources. This does not rule them out — check with a pharmacist.
Is yellow-fruit moonseed a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
- T2 Potential Antimicrobe Producer of Endophytic Bacteria from Yellow Root Plant (Arcangelisia flava (L.)) Originated from Enggano Island. literature abstract metadata
- T2 Antifungal Potential of Secondary Metabolites Derived from Arcangelisia flava (L.) Merr.: An Analysis of In Silico Enzymatic Inhibition and In Vitro Efficacy against Candida Species. literature abstract metadata
- T2 Inhibition of nitric oxide production in RAW 264.7 cells and cytokines IL-1β in osteoarthritis rat models of 70 % ethanol extract of Arcangelisia flava (L.) merr stems. literature abstract metadata
- T2 Exploring the Therapeutic Potential of Oxo berberine Compound in Arcangelisia flava Root Extract for Breast Cancer Treatment: Metabolite Profiling, Pharmacological Network Analysis, and In Silico and In Vitro Evaluation. literature abstract metadata