Japanese cleyera
Ardisia japonica
Ardisia japonica, a plant traditionally used in certain Asian herbal practices but with no specific recorded uses, has been the subject of modern scientific investigation. The plant contains a variety of bioactive compounds including phenols, bergenin derivatives, flavonoids, and triterpenoid saponins, which have shown promising anti-inflammatory, hepatoprotective, and antibacterial effects. These findings support its traditional use in treating respiratory diseases and liver disorders, though the evidence is currently limited to preliminary studies. The biosynthetic pathway of bergenin has been elucidated, and it has potential applications in chronic obstructive pulmonary disease (COPD) treatment through gene expression analysis and functional studies. No significant safety concerns or drug interactions have been reported for Ardisia japonica, but further research is needed to confirm its efficacy and broaden the understanding of its therapeutic potential.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- 42 compounds, including phenols, bergenin derivatives, flavonoids, and triterpenoid saponins, were identified in Ardisia japonica using UHPLC-Q-Orbitrap HRMS.
- The study elucidates the biosynthetic pathway of bergenin in Ardisia japonica and reconstructs it in E. coli, improving bergenin production.
- Ardisia japonica shows various bioactivities including anti-inflammatory, hepatoprotective, and antibacterial effects, supporting its traditional use in treating respiratory diseases and liver disorders.
- HK2 and PTAFR emerged as critical genes for chronic obstructive pulmonary disease treatment based on gene expression analysis and functional enrichment.
Frequently asked questions
What is Japanese cleyera?
Japanese cleyera (Ardisia japonica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Japanese cleyera?
4 sourced findings are recorded for Japanese cleyera; the strongest carries evidence grade A. For example: 42 compounds, including phenols, bergenin derivatives, flavonoids, and triterpenoid saponins, were identified in Ardisia japonica using UHPLC-Q-Orbitrap HRMS.
How strong is the evidence for Japanese cleyera?
The strongest finding for Japanese cleyera carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Japanese cleyera safe? What are the side effects?
No major safety issues are recorded for Japanese cleyera in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Japanese cleyera interact with medications?
No drug interactions are recorded for Japanese cleyera in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Japanese cleyera?
Japanese cleyera is also known as: Ардизия японская.
Is Japanese cleyera a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Unravelling and reconstructing the biosynthetic pathway of bergenin. literature abstract metadata
- T2 Ardisia japonica (Thunb.) Blume and Lespedeza cuneata G. Don may treat chronic obstructive pulmonary disease by targeting HK2 and PTAFR. literature abstract metadata
- T2 Ardisia japonica (Thunb.) Blume: Traditional applications, phytochemistry, pharmacological activities, network pharmacology, and quality control. literature abstract metadata
- T2 Rapid identification of chemical constituents from Ardisia japonica (Thunb.) Blume by ultra-high performance liquid chromatography coupled to quadrupole Orbitrap high-resolution mass spectrometry. literature abstract metadata