slender Dutchman's pipe
Aristolochia debilis
Aristolochia debilis is a plant traditionally used in traditional Chinese medicine. While specific uses of this plant are not well-documented, studies have highlighted its role in biosynthesis and potential for metabolic engineering. Scientific evidence suggests that the plant contains enzymes involved in the production of benzylisoquinoline alkaloids, which could be significant for evaluating nephrotoxicity in complex herbal mixtures. Notably, research has also shown that interactions between two specialist butterfly species and Aristolochia debilis can vary, influencing their larval food demands. Safety concerns are currently minimal, with no major issues or drug interactions recorded.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study confirmed the applicability of zebrafish larvae for evaluating aristolochic acid-related nephrotoxicity in complex traditional Chinese medicine samples.
- The study found that the larval food demand of two specialist butterflies asymmetrically affected their interaction on Aristolochia debilis.
- Two O-methyltransferases from Aristolochia debilis were characterized, showing specific roles in benzylisoquinoline alkaloid biosynthesis.
- Two putative norlaudanosoline methyltransferases from Aristolochia debilis were identified, potentially enabling AA-free Aristolochia herbs through metabolic engineering.
Frequently asked questions
What is slender Dutchman's pipe?
slender Dutchman's pipe (Aristolochia debilis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about slender Dutchman's pipe?
4 sourced findings are recorded for slender Dutchman's pipe; the strongest carries evidence grade D. For example: The study confirmed the applicability of zebrafish larvae for evaluating aristolochic acid-related nephrotoxicity in complex traditional Chinese medicine samples.
How strong is the evidence for slender Dutchman's pipe?
The strongest finding for slender Dutchman's pipe carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is slender Dutchman's pipe safe? What are the side effects?
No major safety issues are recorded for slender Dutchman's pipe in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does slender Dutchman's pipe interact with medications?
No drug interactions are recorded for slender Dutchman's pipe in our sources. This does not rule them out — check with a pharmacist.
Is slender Dutchman's pipe a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Characterization of two putative norlaudanosoline methyltransferases from Aristolochia debilis. literature abstract metadata
- T2 Asymmetric interactions between two butterfly species mediated by food demand. literature abstract metadata
- T2 Investigation of the applicability of the zebrafish model for the evaluation of aristolochic acid-related nephrotoxicity. literature abstract metadata
- T2 Molecular characterization of two O-methyltransferases involved in benzylisoquinoline alkaloid biosynthesis in Aristolochia debilis. literature abstract metadata