Annual Mugwort
Artemisia annua
Artemisia annua, commonly known as sweet wormwood or annual wormwood, is a traditional plant with roots in East Asian medicine. Traditionally, it has been used to treat various ailments, including fever and malaria, though specific uses vary across different traditions. Scientific evidence suggests that quercetin, an active component of Artemisia annua, may alleviate psoriasis by regulating ferroptosis and potentially modulating the P53/SAT1/ALOX15 pathway. Additionally, studies indicate that Artemisia annua contains artemisinin, a compound effective against malaria, with varying levels found between geographical locations. While commercial supplements show inconsistent artemisinin levels, genetic markers have been identified to support marker-assisted selection for improved production. No major safety issues or drug interactions have been recorded, but further research is needed to fully understand its potential benefits and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This study suggests that quercetin, an active component of Artemisia annua, alleviates psoriasis by regulating ferroptosis and potentially modulating the P53/SAT1/ALOX15 pathway.
- The study identified Artemisia annua as a promising source of biologically active sesquiterpene γ-lactones, relevant to the production of antimalarial preparations.
- Artemisinin content varied between geographical locations and commercial supplements showed inconsistent artemisinin levels.
- This study identified genetic markers associated with higher artemisinin content in Artemisia annua, supporting marker-assisted selection for improved production.
- The study found that glyoxalase gene families in Artemisia annua are upregulated under salinity stress, linking MG detoxification with redox regulation and secondary metabolite production.
Frequently asked questions
What is Annual Mugwort?
Annual Mugwort (Artemisia annua) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Annual Mugwort?
5 sourced findings are recorded for Annual Mugwort; the strongest carries evidence grade D. For example: This study suggests that quercetin, an active component of Artemisia annua, alleviates psoriasis by regulating ferroptosis and potentially modulating the P53/SAT1/ALOX15 pathway.
How strong is the evidence for Annual Mugwort?
The strongest finding for Annual Mugwort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Annual Mugwort safe? What are the side effects?
No major safety issues are recorded for Annual Mugwort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Annual Mugwort interact with medications?
No drug interactions are recorded for Annual Mugwort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Annual Mugwort?
Annual Mugwort is also known as: Полынь однолетняя, Armoise annuelle.
Is Annual Mugwort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Sesquiterpene γ-lactones of plants of the Asteraceae family of the flora of Kazakhstan: Search, distribution, biological activity. literature abstract metadata
- T2 Deciphering glyoxalase gene families and their coordinated regulation with the ascorbate-glutathione cycle during salinity stress in Artemisia annua. literature abstract metadata
- T2 Characterization of high-artemisinin yielding Artemisia annua bioecotypes using gene-specific STS markers and HPLC for quality-oriented selection. literature abstract metadata
- T2 Mechanism of Artemisia annua active component quercetin in treating psoriasis by regulating ferroptosis. literature abstract metadata
- T2 Phytochemical Composition of Clonally Propagated Artemisia annua L. in Different Geographical Locations and Its Commercial Supplement Quality. literature abstract metadata