American paw paw
Asimina triloba
Asimina triloba, commonly known as the pawpaw tree, is native to North America. While traditional medicinal uses are not well-documented, recent scientific research has highlighted its potential in various fields. Studies have shown that a novel cyclopeptide from Asimina triloba, when encapsulated in nanoparticles, demonstrated enhanced efficacy against triple-negative breast cancer both in vitro and in vivo. Additionally, a polysaccharide extracted from the fruits of this tree showed promise in alleviating symptoms of ulcerative colitis by modulating inflammatory signaling and gut microbiota. The genetic resources derived from Asimina triloba's genome assembly have also provided valuable insights for future research. Notably, no major safety issues or drug interactions have been recorded to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study provides evidence for a late-acting self-incompatibility system in Asimina triloba, involving arrested embryo development and fruitlet abscission following auto-incompatible pollination.
- The study produced the first high-quality genome assembly of the pawpaw tree (Asimina triloba), providing genetic resources for future research.
- The study found that a novel cyclopeptide from Asimina triloba, encapsulated in nanoparticles, showed enhanced efficacy against triple-negative breast cancer in vitro and in vivo.
- A polysaccharide from Asimina triloba fruits showed promise in alleviating symptoms of ulcerative colitis by modulating inflammatory signaling and gut microbiota.
Frequently asked questions
What is American paw paw?
American paw paw (Asimina triloba) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about American paw paw?
4 sourced findings are recorded for American paw paw; the strongest carries evidence grade D. For example: The study provides evidence for a late-acting self-incompatibility system in Asimina triloba, involving arrested embryo development and fruitlet abscission following auto-incompatible pollination.
How strong is the evidence for American paw paw?
The strongest finding for American paw paw carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is American paw paw safe? What are the side effects?
No major safety issues are recorded for American paw paw in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does American paw paw interact with medications?
No drug interactions are recorded for American paw paw in our sources. This does not rule them out — check with a pharmacist.
What are the common names of American paw paw?
American paw paw is also known as: Азимина трёхлопастная, asiminier trilobé.
Is American paw paw a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Polysaccharide from Asimina triloba fruits alleviates DSS-induced ulcerative colitis by modulating inflammatory signaling and gut microbiota. literature abstract metadata
- T2 Late-acting self-incompatibility in Asimina triloba: implications for the evolution of self-incompatibility in angiosperms. literature abstract metadata
- T2 Enhanced Anticancer Efficacy of Novel Asiminatide A Isolated from Asimina triloba in Triple-Negative Breast Cancer. literature abstract metadata
- T2 First genome and transcription factor profile for Asimina triloba, a native North American fruit tree. literature abstract metadata